CYTK vs ORI

Comparison between Cytokinetics Inc (CYTK, Company) and Old Republic International Corp (ORI, Company).

CYTK is from the Healthcare sector, while ORI is from the Financial Services sector.

5-Year PerformanceCYTK has outperformed ORI, delivering a return of +27.9% compared to +17.3%

CYTK vs ORI - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	CYTK(COMPANY)	ORI(COMPANY)
Market Cap	$9.71B	$9.68B
Max Drawdown	97.09%	69.46%
Sharpe Ratio	1.73	0.58
5Y Beta	0.78	0.42
Industry	Biotechnology	Insurance - Property & Casualty
P/E Ratio	-11.51	9.18
Forward P/E	117.65	11.43
PEG Ratio	-0.40	0.20
Dividend Yield	N/A	2.99%
5Y Dividends CAGR	N/A	16.53%
5Y EPS CAGR	27.73%	4.07%
Debt to Equity	-126.00%	0.00%
Free Cash Flow Yield	-5.65%	12.54%
P/S Ratio	101.07	1.03
P/B Ratio	60.31	1.63

Market Cap

Winner

CYTK

$9.71B

ORI

$9.68B

Max Drawdown

CYTK

97.09%

Winner

ORI

69.46%

Sharpe Ratio

Winner

CYTK

1.73

ORI

0.58

5Y Beta

CYTK

0.78

Winner

ORI

0.42

Industry

CYTK

Biotechnology

ORI

Insurance - Property & Casualty

P/E Ratio

Winner

CYTK

-11.51

ORI

9.18

Forward P/E

CYTK

117.65

Winner

ORI

11.43

PEG Ratio

Winner

CYTK

-0.40

ORI

0.20

Dividend Yield

CYTK

N/A

ORI

2.99%

5Y Dividends CAGR

CYTK

N/A

ORI

16.53%

5Y EPS CAGR

Winner

CYTK

27.73%

ORI

4.07%

Debt to Equity

Winner

CYTK

-126.00%

ORI

0.00%

Free Cash Flow Yield

CYTK

-5.65%

Winner

ORI

12.54%

P/S Ratio

CYTK

101.07

Winner

ORI

1.03

P/B Ratio

CYTK

60.31

Winner

ORI

1.63

CYTK vs ORI - Historical Returns

Returns include dividend reinvestment.

Period	CYTK	ORI
1 month	+23.85%	-2.04%
3 months	+21.81%	-6.97%
6 months	+11.94%	-8.87%
1 year	+149.89%	+13.53%
5 years(CAGR)	+27.94%	+17.31%
10 years(CAGR)	+25.18%	+15.65%
Max(CAGR)	-1.06%	+12.77%

Winner

CYTK

+23.85%

ORI

-2.04%

Winner

CYTK

+21.81%

ORI

-6.97%

Winner

CYTK

+11.94%

ORI

-8.87%

Winner

CYTK

+149.89%

ORI

+13.53%

5Y(CAGR)

Winner

CYTK

+27.94%

ORI

+17.31%

10Y(CAGR)

Winner

CYTK

+25.18%

ORI

+15.65%

Max(CAGR)

CYTK

-1.06%

Winner

ORI

+12.77%

CYTK vs ORI - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	CYTK	ORI
2026	+23.59%	-8.22%
2025	+29.86%	+38.05%
2024	-44.08%	+26.86%
2023	+88.25%	+26.15%
2022	-0.39%	+7.85%
2021	+133.03%	+48.34%
2020	+96.97%	-7.50%
2019	+55.57%	+20.11%
2018	-27.77%	+6.33%
2017	-34.27%	+16.42%
2016	+21.50%	+7.92%
2015	+41.93%	+33.55%
2014	+19.20%	-10.10%
2013	+61.64%	+66.97%
2012	-32.65%	+25.32%
2011	-55.56%	-28.23%
2010	-32.80%	+41.56%
2009	+2.11%	-9.63%
2008	-37.36%	-16.29%
2007	-43.29%	-32.22%
2006	+19.30%	+10.88%
2005	-33.33%	+11.39%
2004	-36.34%	+2.13%
2003	N/A	+36.38%
2002	N/A	+1.48%
2001	N/A	-4.79%
2000	N/A	+151.43%
1999	N/A	+2.01%

CYTK vs ORI Drawdown Comparison

The maximum drawdown for CYTK was -97.09%, occurring on Oct 10, 2014. Recovery took 4952 trading sessions.

The maximum drawdown for ORI was -66.22%, occurring on Nov 20, 2008. Recovery took 1712 trading sessions.

The current CYTK drawdown is -29.40%. The current ORI drawdown is -9.89%.

Rank	CYTK	ORI
#1	-97.09% May 5, 2004 - Jan 8, 2024	-66.22% Jan 3, 2007 - Oct 21, 2013
#2	-72.39% Jan 8, 2024 - May 15, 2025	-47.79% Oct 21, 2019 - Mar 10, 2021
#3	-1.52% May 3, 2004 - May 5, 2004	-28.07% Dec 28, 2000 - Feb 27, 2002
#4	N/A	-27.08% Apr 12, 2002 - May 30, 2003
#5	N/A	-21.84% Nov 5, 1999 - Apr 26, 2000
#6	N/A	-21.04% Jan 26, 2004 - Sep 12, 2005
#7	N/A	-20.36% Feb 16, 2022 - Jan 6, 2023
#8	N/A	-19.63% Sep 19, 2000 - Oct 27, 2000
#9	N/A	-18.86% Jun 18, 2014 - Jul 28, 2015
#10	N/A	-16.21% Jul 22, 2016 - Jan 26, 2017
#11	N/A	-14.88% Dec 31, 2013 - May 28, 2014
#12	N/A	-13.93% Dec 3, 2018 - May 22, 2019
#13	N/A	-13.92% Dec 24, 2025 - Jan 23, 2026
#14	N/A	-13.51% Sep 21, 2018 - Dec 3, 2018
#15	N/A	-13.33% Oct 30, 2000 - Dec 5, 2000