CYTK vs ICLR

Comparison between Cytokinetics Inc (CYTK, Company) and Icon Plc (ICLR, Company).

Both CYTK and ICLR are from the Healthcare sector.

5-Year PerformanceCYTK has outperformed ICLR, delivering a return of +24.8% compared to -12.6%

CYTK vs ICLR - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	CYTK(COMPANY)	ICLR(COMPANY)
Market Cap	$9.52B	$9.48B
Max Drawdown	97.09%	76.87%
Sharpe Ratio	1.77	0.06
5Y Beta	0.80	1.06
Industry	Biotechnology	Diagnostics & Research
P/E Ratio	-11.28	11.98
Forward P/E	117.65	10.33
PEG Ratio	-0.39	0.37
5Y EPS CAGR	27.73%	22.96%
Debt to Equity	-126.00%	35.67%
Free Cash Flow Yield	-5.77%	11.80%
P/S Ratio	99.08	1.13
P/B Ratio	60.31	1.02

Market Cap

Winner

CYTK

$9.52B

ICLR

$9.48B

Max Drawdown

CYTK

97.09%

Winner

ICLR

76.87%

Sharpe Ratio

Winner

CYTK

1.77

ICLR

0.06

5Y Beta

Winner

CYTK

0.80

ICLR

1.06

Industry

CYTK

Biotechnology

ICLR

Diagnostics & Research

P/E Ratio

Winner

CYTK

-11.28

ICLR

11.98

Forward P/E

CYTK

117.65

Winner

ICLR

10.33

PEG Ratio

Winner

CYTK

-0.39

ICLR

0.37

5Y EPS CAGR

Winner

CYTK

27.73%

ICLR

22.96%

Debt to Equity

Winner

CYTK

-126.00%

ICLR

35.67%

Free Cash Flow Yield

CYTK

-5.77%

Winner

ICLR

11.80%

P/S Ratio

CYTK

99.08

Winner

ICLR

1.13

P/B Ratio

CYTK

60.31

Winner

ICLR

1.02

CYTK vs ICLR - Historical Returns

Returns include dividend reinvestment.

Period	CYTK	ICLR
1 month	+18.52%	+3.56%
3 months	+18.68%	+25.90%
6 months	+18.36%	-27.80%
1 year	+162.13%	-11.45%
5 years(CAGR)	+24.85%	-12.57%
10 years(CAGR)	+26.49%	+6.30%
Max(CAGR)	-0.93%	+14.30%

Winner

CYTK

+18.52%

ICLR

+3.56%

CYTK

+18.68%

Winner

ICLR

+25.90%

Winner

CYTK

+18.36%

ICLR

-27.80%

Winner

CYTK

+162.13%

ICLR

-11.45%

5Y(CAGR)

Winner

CYTK

+24.85%

ICLR

-12.57%

10Y(CAGR)

Winner

CYTK

+26.49%

ICLR

+6.30%

Max(CAGR)

CYTK

-0.93%

Winner

ICLR

+14.30%

CYTK vs ICLR - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	CYTK	ICLR
2026	+27.39%	-37.94%
2025	+29.86%	-14.30%
2024	-44.08%	-25.32%
2023	+88.25%	+46.22%
2022	-0.39%	-34.38%
2021	+133.03%	+61.29%
2020	+96.97%	+15.01%
2019	+55.57%	+34.83%
2018	-27.77%	+12.87%
2017	-34.27%	+50.11%
2016	+21.50%	+0.82%
2015	+41.93%	+50.55%
2014	+19.20%	+27.60%
2013	+61.64%	+43.32%
2012	-32.65%	+60.74%
2011	-55.56%	-21.76%
2010	-32.80%	+1.34%
2009	+2.11%	+13.18%
2008	-37.36%	-36.40%
2007	-43.29%	+58.86%
2006	+19.30%	+83.68%
2005	-33.33%	+8.26%
2004	-36.34%	-11.32%
2003	N/A	+55.60%
2002	N/A	-5.74%
2001	N/A	+86.31%
2000	N/A	+0.76%
1999	N/A	+25.93%

CYTK vs ICLR Drawdown Comparison

The maximum drawdown for CYTK was -97.09%, occurring on Oct 10, 2014. Recovery took 4952 trading sessions.

The maximum drawdown for ICLR was -76.87%, occurring on Feb 12, 2026. This drawdown has not yet recovered.

The current CYTK drawdown is -27.23%. The current ICLR drawdown is -66.18%.

Rank	CYTK	ICLR
#1	-97.09% May 5, 2004 - Jan 8, 2024	-76.87% Jul 16, 2024 - Feb 12, 2026
#2	-72.39% Jan 8, 2024 - May 15, 2025	-67.73% Aug 11, 2008 - Feb 7, 2014
#3	-1.52% May 3, 2004 - May 5, 2004	-60.60% Jul 19, 2001 - Oct 1, 2003
#4	N/A	-43.85% Dec 31, 2021 - Feb 22, 2024
#5	N/A	-42.39% Feb 9, 2000 - Jan 29, 2001
#6	N/A	-34.57% Feb 19, 2020 - Jul 14, 2020
#7	N/A	-33.62% Jan 9, 2004 - Sep 28, 2005
#8	N/A	-32.60% Feb 13, 2001 - Jun 5, 2001
#9	N/A	-26.02% Sep 30, 2005 - Apr 20, 2006
#10	N/A	-24.35% Aug 10, 2015 - Oct 20, 2016
#11	N/A	-24.11% Nov 19, 1999 - Dec 29, 1999
#12	N/A	-22.96% Mar 19, 2014 - Jul 30, 2014
#13	N/A	-22.36% Sep 28, 2018 - Jun 28, 2019
#14	N/A	-22.22% Jan 20, 2021 - May 5, 2021
#15	N/A	-15.81% Feb 25, 2008 - Apr 29, 2008