CTMX vs HELE

Comparison between CytomX Therapeutics Inc (CTMX, Company) and Helen of Troy Ltd (HELE, Company).

CTMX is from the Healthcare sector, while HELE is from the Consumer Defensive sector.

5-Year PerformanceCTMX has outperformed HELE, delivering a return of -10.3% compared to -34.3%

CTMX vs HELE - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	CTMX(COMPANY)	HELE(COMPANY)
Market Cap	$652M	$653M
Max Drawdown	98.74%	94.72%
Sharpe Ratio	0.79	0.61
5Y Beta	2.01	1.10
Industry	Biotechnology	Household & Personal Products
P/E Ratio	24.82	-1.56
Forward P/E	14.20	8.01
PEG Ratio	0.76	-0.07
Debt to Equity	0.00%	84.90%
Free Cash Flow Yield	-12.33%	17.17%
P/S Ratio	22.42	0.37
P/B Ratio	2.48	0.78

Market Cap

CTMX

$652M

Winner

HELE

$653M

Max Drawdown

CTMX

98.74%

Winner

HELE

94.72%

Sharpe Ratio

Winner

CTMX

0.79

HELE

0.61

5Y Beta

CTMX

2.01

Winner

HELE

1.10

Industry

CTMX

Biotechnology

HELE

Household & Personal Products

P/E Ratio

CTMX

24.82

Winner

HELE

-1.56

Forward P/E

CTMX

14.20

Winner

HELE

8.01

PEG Ratio

CTMX

0.76

Winner

HELE

-0.07

Debt to Equity

Winner

CTMX

0.00%

HELE

84.90%

Free Cash Flow Yield

CTMX

-12.33%

Winner

HELE

17.17%

P/S Ratio

CTMX

22.42

Winner

HELE

0.37

P/B Ratio

CTMX

2.48

Winner

HELE

0.78

CTMX vs HELE - Historical Returns

Returns include dividend reinvestment.

Period	CTMX	HELE
1 month	+12.50%	+4.92%
3 months	-28.15%	+34.58%
6 months	-35.35%	+42.53%
1 year	+43.70%	+25.77%
5 years(CAGR)	-10.30%	-34.33%
10 years(CAGR)	-10.65%	-12.10%
Max(CAGR)	-11.58%	+4.21%

Winner

CTMX

+12.50%

HELE

+4.92%

CTMX

-28.15%

Winner

HELE

+34.58%

CTMX

-35.35%

Winner

HELE

+42.53%

Winner

CTMX

+43.70%

HELE

+25.77%

5Y(CAGR)

Winner

CTMX

-10.30%

HELE

-34.33%

10Y(CAGR)

Winner

CTMX

-10.65%

HELE

-12.10%

Max(CAGR)

CTMX

-11.58%

Winner

HELE

+4.21%

CTMX vs HELE - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	CTMX	HELE
2026	-19.53%	+32.36%
2025	+301.89%	-64.30%
2024	-39.05%	-50.99%
2023	-3.73%	+9.05%
2022	-64.37%	-54.68%
2021	-36.14%	+11.02%
2020	-23.79%	+21.20%
2019	-46.80%	+37.99%
2018	-30.61%	+36.72%
2017	+97.11%	+12.36%
2016	-46.29%	-6.11%
2015	+61.78%	+45.47%
2014	N/A	+33.92%
2013	N/A	+45.15%
2012	N/A	+5.86%
2011	N/A	+0.10%
2010	N/A	+23.40%
2009	N/A	+38.27%
2008	N/A	+5.53%
2007	N/A	-31.77%
2006	N/A	+49.57%
2005	N/A	-51.37%
2004	N/A	+45.81%
2003	N/A	+94.45%
2002	N/A	-5.98%
2001	N/A	+134.99%
2000	N/A	-32.76%
1999	N/A	-20.00%

CTMX vs HELE Drawdown Comparison

The maximum drawdown for CTMX was -98.74%, occurring on Apr 7, 2025. This drawdown has not yet recovered.

The maximum drawdown for HELE was -94.72%, occurring on Mar 27, 2026. This drawdown has not yet recovered.

The current CTMX drawdown is -90.01%. The current HELE drawdown is -89.62%.

Rank	CTMX	HELE
#1	-98.74% Mar 12, 2018 - Apr 7, 2025	-94.72% Jan 27, 2021 - Mar 27, 2026
#2	-60.90% Dec 4, 2015 - Jan 5, 2018	-76.82% Jul 2, 2004 - Feb 12, 2013
#3	-29.86% Oct 14, 2015 - Nov 17, 2015	-61.08% Nov 26, 1999 - Jul 12, 2001
#4	-4.42% Oct 8, 2015 - Oct 14, 2015	-45.07% Feb 11, 2020 - Jul 9, 2020
#5	-4.10% Mar 7, 2018 - Mar 9, 2018	-43.39% Jul 23, 2001 - Jan 8, 2002
#6	-3.64% Feb 7, 2018 - Feb 14, 2018	-42.94% Jan 15, 2002 - May 13, 2003
#7	-2.80% Jan 29, 2018 - Feb 6, 2018	-25.99% Jun 8, 2016 - Jul 9, 2018
#8	-2.59% Mar 2, 2018 - Mar 7, 2018	-25.43% Mar 18, 2014 - Jan 9, 2015
#9	-2.50% Nov 19, 2015 - Nov 23, 2015	-24.87% Sep 4, 2003 - Jan 13, 2004
#10	-2.17% Jan 22, 2018 - Jan 29, 2018	-24.59% Dec 3, 2018 - Jul 10, 2019
#11	-2.13% Jan 5, 2018 - Jan 9, 2018	-20.53% Dec 4, 2015 - Mar 29, 2016
#12	-1.95% Dec 2, 2015 - Dec 4, 2015	-17.30% Jun 25, 2015 - Oct 9, 2015
#13	-1.35% Jan 12, 2018 - Jan 17, 2018	-15.70% May 4, 2004 - Jun 30, 2004
#14	-0.89% Feb 14, 2018 - Feb 22, 2018	-12.61% Aug 24, 2020 - Dec 8, 2020
#15	-0.39% Jan 17, 2018 - Jan 22, 2018	-11.75% Mar 1, 2004 - Apr 6, 2004