CRL vs NUVL

Comparison between Charles River Laboratories International Inc (CRL, Company) and Nuvalent Inc - Class A (NUVL, Company).

Both CRL and NUVL are from the Healthcare sector.

5-Year PerformanceNUVL has outperformed CRL, delivering a return of +46.8% compared to -10.1%

CRL vs NUVL - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	CRL(COMPANY)	NUVL(COMPANY)
Market Cap	$9.74B	$9.72B
Max Drawdown	78.23%	80.70%
Sharpe Ratio	0.93	1.02
5Y Beta	1.37	0.98
Industry	Diagnostics & Research	Biotechnology
P/E Ratio	-53.78	-21.86
Forward P/E	18.15	N/A
PEG Ratio	-0.08	-0.34
Debt to Equity	0.23%	0.00%
Free Cash Flow Yield	6.24%	-3.22%
P/S Ratio	2.42	N/A
P/B Ratio	3.31	8.33

Market Cap

Winner

CRL

$9.74B

NUVL

$9.72B

Max Drawdown

Winner

CRL

78.23%

NUVL

80.70%

Sharpe Ratio

CRL

0.93

Winner

NUVL

1.02

5Y Beta

CRL

1.37

Winner

NUVL

0.98

Industry

CRL

Diagnostics & Research

NUVL

Biotechnology

P/E Ratio

Winner

CRL

-53.78

NUVL

-21.86

Forward P/E

CRL

18.15

NUVL

N/A

PEG Ratio

CRL

-0.08

Winner

NUVL

-0.34

Debt to Equity

CRL

0.23%

Winner

NUVL

0.00%

Free Cash Flow Yield

Winner

CRL

6.24%

NUVL

-3.22%

P/S Ratio

CRL

2.42

NUVL

N/A

P/B Ratio

Winner

CRL

3.31

NUVL

8.33

CRL vs NUVL - Historical Returns

Returns include dividend reinvestment.

Period	CRL	NUVL
1 month	+37.64%	+17.69%
3 months	+30.64%	+25.96%
6 months	+5.92%	+18.66%
1 year	+42.30%	+56.10%
5 years(CAGR)	-10.12%	+46.82%
10 years(CAGR)	+11.01%	N/A
Max(CAGR)	+9.18%	+46.82%

Winner

CRL

+37.64%

NUVL

+17.69%

Winner

CRL

+30.64%

NUVL

+25.96%

CRL

+5.92%

Winner

NUVL

+18.66%

CRL

+42.30%

Winner

NUVL

+56.10%

5Y(CAGR)

CRL

-10.12%

Winner

NUVL

+46.82%

10Y(CAGR)

CRL

+11.01%

NUVL

N/A

Max(CAGR)

CRL

+9.18%

Winner

NUVL

+46.82%

CRL vs NUVL - Annual Returns (2000 - 2026)

Returns include dividend reinvestment.

Year	CRL	NUVL
2026	+6.57%	+22.49%
2025	+9.22%	+25.75%
2024	-21.20%	+2.86%
2023	+8.24%	+154.02%
2022	-39.82%	+60.19%
2021	+50.91%	+1.55%
2020	+62.36%	N/A
2019	+37.51%	N/A
2018	+2.29%	N/A
2017	+43.02%	N/A
2016	-2.63%	N/A
2015	+25.85%	N/A
2014	+20.35%	N/A
2013	+39.43%	N/A
2012	+35.03%	N/A
2011	-23.74%	N/A
2010	+5.87%	N/A
2009	+25.29%	N/A
2008	-59.80%	N/A
2007	+52.17%	N/A
2006	+1.38%	N/A
2005	-6.57%	N/A
2004	+35.16%	N/A
2003	-10.95%	N/A
2002	+18.44%	N/A
2001	+28.13%	N/A
2000	+24.45%	N/A

CRL vs NUVL Drawdown Comparison

The maximum drawdown for CRL was -78.23%, occurring on Apr 11, 2025. This drawdown has not yet recovered.

The maximum drawdown for NUVL was -80.70%, occurring on May 16, 2022. Recovery took 414 trading sessions.

The current CRL drawdown is -52.93%. The current NUVL drawdown is -0.05%.

Rank	CRL	NUVL
#1	-78.23% Sep 24, 2021 - Apr 11, 2025	-80.70% Sep 7, 2021 - May 1, 2023
#2	-69.81% Aug 19, 2008 - Jan 13, 2015	-47.12% Sep 16, 2024 - Jun 9, 2026
#3	-47.06% Sep 29, 2000 - Jul 2, 2001	-29.48% Feb 27, 2024 - Sep 9, 2024
#4	-44.54% Feb 19, 2020 - May 29, 2020	-22.09% Oct 6, 2023 - Nov 30, 2023
#5	-39.60% Oct 23, 2002 - Feb 11, 2004	-17.53% Jul 31, 2023 - Oct 4, 2023
#6	-35.65% Jul 20, 2005 - May 30, 2007	-16.05% Aug 4, 2021 - Aug 17, 2021
#7	-34.97% Aug 8, 2000 - Sep 29, 2000	-12.44% Jun 15, 2023 - Jul 20, 2023
#8	-26.85% Mar 19, 2015 - May 20, 2016	-12.17% Dec 15, 2023 - Feb 8, 2024
#9	-25.67% Oct 11, 2001 - May 15, 2002	-8.47% Sep 9, 2024 - Sep 16, 2024
#10	-23.79% Aug 1, 2016 - Feb 14, 2017	-7.64% May 1, 2023 - May 9, 2023
#11	-23.62% Dec 3, 2018 - Feb 13, 2019	-6.21% Jun 2, 2023 - Jun 15, 2023
#12	-23.12% Jun 19, 2002 - Aug 14, 2002	-5.13% May 22, 2023 - May 30, 2023
#13	-21.17% Jan 10, 2008 - Aug 15, 2008	-4.90% Feb 16, 2024 - Feb 23, 2024
#14	-19.86% Aug 24, 2001 - Oct 10, 2001	-4.47% May 15, 2023 - May 22, 2023
#15	-16.93% Apr 3, 2019 - Dec 17, 2019	-3.65% Feb 12, 2024 - Feb 14, 2024

Correlation

Correlation between CRL and NUVL is -0.54 which considered as a moderate negative correlation - the stocks show some tendency to move in opposite directions.

-0.54

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