CRBU vs ACHV

Comparison between Caribou Biosciences Inc (CRBU, Company) and Achieve Life Sciences Inc (ACHV, Company).

Both CRBU and ACHV are from the Healthcare sector.

5-Year PerformanceACHV has outperformed CRBU, delivering a return of -8.7% compared to -37.9%

CRBU vs ACHV - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	CRBU(COMPANY)	ACHV(COMPANY)
Market Cap	$174M	$174M
Max Drawdown	97.58%	100.00%
Sharpe Ratio	0.73	0.90
5Y Beta	1.89	0.00
Industry	Biotechnology	Biotechnology
P/E Ratio	-1.27	-2.78
Forward P/E	N/A	35.34
PEG Ratio	N/A	-1.73
5Y EPS CAGR	N/A	-20.82%
Debt to Equity	0.00%	17.21%
Free Cash Flow Yield	-58.82%	-28.50%
P/S Ratio	15.23	5.09
P/B Ratio	1.73	7.99

Market Cap

CRBU

$174M

Winner

ACHV

$174M

Max Drawdown

Winner

CRBU

97.58%

ACHV

100.00%

Sharpe Ratio

CRBU

0.73

Winner

ACHV

0.90

5Y Beta

CRBU

1.89

Winner

ACHV

0.00

Industry

CRBU

Biotechnology

ACHV

Biotechnology

P/E Ratio

CRBU

-1.27

Winner

ACHV

-2.78

Forward P/E

CRBU

N/A

ACHV

35.34

PEG Ratio

CRBU

N/A

ACHV

-1.73

5Y EPS CAGR

CRBU

N/A

ACHV

-20.82%

Debt to Equity

Winner

CRBU

0.00%

ACHV

17.21%

Free Cash Flow Yield

CRBU

-58.82%

Winner

ACHV

-28.50%

P/S Ratio

CRBU

15.23

Winner

ACHV

5.09

P/B Ratio

Winner

CRBU

1.73

ACHV

7.99

CRBU vs ACHV - Historical Returns

Returns include dividend reinvestment.

Period	CRBU	ACHV
1 month	-21.43%	-7.85%
3 months	-15.61%	+33.33%
6 months	-10.89%	+18.97%
1 year	+37.50%	+66.27%
5 years(CAGR)	-37.86%	-8.71%
10 years(CAGR)	N/A	-45.28%
Max(CAGR)	-37.86%	-31.52%

CRBU

-21.43%

Winner

ACHV

-7.85%

CRBU

-15.61%

Winner

ACHV

+33.33%

CRBU

-10.89%

Winner

ACHV

+18.97%

CRBU

+37.50%

Winner

ACHV

+66.27%

5Y(CAGR)

CRBU

-37.86%

Winner

ACHV

-8.71%

10Y(CAGR)

CRBU

N/A

ACHV

-45.28%

Max(CAGR)

CRBU

-37.86%

Winner

ACHV

-31.52%

CRBU vs ACHV - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	CRBU	ACHV
2026	+0.31%	+11.07%
2025	-5.36%	+34.69%
2024	-71.45%	-15.59%
2023	-13.31%	+62.85%
2022	-59.01%	-70.34%
2021	-7.54%	-1.52%
2020	N/A	-22.10%
2019	N/A	-58.59%
2018	N/A	-91.60%
2017	N/A	-76.06%
2016	N/A	-57.27%
2015	N/A	-47.84%
2014	N/A	-74.56%
2013	N/A	-37.71%
2012	N/A	+10.34%
2011	N/A	-30.24%
2010	N/A	-23.12%
2009	N/A	+536.57%
2008	N/A	-62.96%
2007	N/A	-92.69%
2006	N/A	+19.10%
2005	N/A	+49.26%
2004	N/A	-30.65%
2003	N/A	+127.80%
2002	N/A	-73.63%
2001	N/A	+1124.24%
2000	N/A	-77.58%
1999	N/A	-24.47%

CRBU vs ACHV Drawdown Comparison

The maximum drawdown for CRBU was -97.58%, occurring on Apr 16, 2025. This drawdown has not yet recovered.

The maximum drawdown for ACHV was -100.00%, occurring on Apr 8, 2025. This drawdown has not yet recovered.

The current CRBU drawdown is -94.73%. The current ACHV drawdown is -100.00%.

Rank	CRBU	ACHV
#1	-97.58% Sep 7, 2021 - Apr 16, 2025	-100.00% Mar 6, 2000 - Apr 8, 2025
#2	-15.94% Aug 23, 2021 - Sep 3, 2021	-43.22% Dec 7, 1999 - Jan 20, 2000
#3	-15.80% Aug 10, 2021 - Aug 23, 2021	-32.93% Nov 1, 1999 - Dec 7, 1999
#4	-5.97% Jul 26, 2021 - Aug 2, 2021	-20.00% Jan 26, 2000 - Feb 18, 2000
#5	-1.77% Aug 2, 2021 - Aug 4, 2021	-14.53% Feb 22, 2000 - Mar 1, 2000
#6	N/A	-6.36% Mar 2, 2000 - Mar 6, 2000