CLSD vs IVF

Comparison between Clearside Biomedical, Inc. Common Stock (CLSD, Company) and INVO Fertility Inc (IVF, Company).

Both CLSD and IVF are from the Healthcare sector.

5-Year PerformanceCLSD has outperformed IVF, delivering a return of -64.5% compared to -90.1%

CLSD vs IVF - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	CLSD(COMPANY)	IVF(COMPANY)
Market Cap	$2.15M	$2.13M
Max Drawdown	99.89%	100.00%
Sharpe Ratio	-1.80	-0.99
5Y Beta	N/A	-0.22
Industry	Biotechnology	Medical Devices
P/E Ratio	-0.08	-0.39
Debt to Equity	0.00%	47.06%
P/S Ratio	0.64	0.39
P/B Ratio	-0.04	0.56

Market Cap

Winner

CLSD

$2.15M

IVF

$2.13M

Max Drawdown

Winner

CLSD

99.89%

IVF

100.00%

Sharpe Ratio

CLSD

-1.80

Winner

IVF

-0.99

5Y Beta

CLSD

N/A

IVF

-0.22

Industry

CLSD

Biotechnology

IVF

Medical Devices

P/E Ratio

CLSD

-0.08

Winner

IVF

-0.39

Debt to Equity

Winner

CLSD

0.00%

IVF

47.06%

P/S Ratio

CLSD

0.64

Winner

IVF

0.39

P/B Ratio

Winner

CLSD

-0.04

IVF

0.56

CLSD vs IVF - Historical Returns

Returns include dividend reinvestment.

Period	CLSD	IVF
1 month	+0.00%	-19.51%
3 months	+0.00%	-60.60%
6 months	+0.00%	-69.79%
1 year	-96.71%	-98.90%
5 years(CAGR)	-64.49%	-90.07%
10 years(CAGR)	-42.40%	-71.59%
Max(CAGR)	-42.58%	-48.16%

Winner

CLSD

+0.00%

IVF

-19.51%

Winner

CLSD

+0.00%

IVF

-60.60%

Winner

CLSD

+0.00%

IVF

-69.79%

Winner

CLSD

-96.71%

IVF

-98.90%

5Y(CAGR)

Winner

CLSD

-64.49%

IVF

-90.07%

10Y(CAGR)

Winner

CLSD

-42.40%

IVF

-71.59%

Max(CAGR)

Winner

CLSD

-42.58%

IVF

-48.16%

CLSD vs IVF - Annual Returns (2012 - 2026)

Returns include dividend reinvestment.

Year	CLSD	IVF
2026	+0.00%	-70.67%
2025	-97.14%	-99.69%
2024	-26.36%	-36.72%
2023	-3.70%	-84.63%
2022	-61.11%	-87.12%
2021	-14.20%	+8.47%
2020	+29.86%	-56.52%
2019	+152.17%	-47.27%
2018	-85.12%	+180.00%
2017	-25.29%	-55.72%
2016	+23.31%	-49.25%
2015	N/A	+169.23%
2014	N/A	+381.48%
2013	N/A	+260.00%
2012	N/A	-60.00%

CLSD vs IVF Drawdown Comparison

The maximum drawdown for CLSD was -99.89%, occurring on Nov 28, 2025. This drawdown has not yet recovered.

The maximum drawdown for IVF was -100.00%, occurring on Jun 8, 2026. This drawdown has not yet recovered.

The current CLSD drawdown is -99.89%. The current IVF drawdown is -100.00%.

Rank	CLSD	IVF
#1	-99.89% Oct 11, 2016 - Nov 28, 2025	-100.00% Nov 4, 2015 - Jun 8, 2026
#2	-17.17% Jun 2, 2016 - Aug 23, 2016	-81.82% Sep 18, 2012 - Nov 15, 2013
#3	-5.93% Sep 28, 2016 - Oct 3, 2016	-63.64% Dec 9, 2013 - Jun 17, 2014
#4	-5.91% Aug 23, 2016 - Aug 30, 2016	-56.00% Jun 17, 2014 - Oct 23, 2014
#5	-5.71% Sep 9, 2016 - Sep 19, 2016	-54.55% Nov 4, 2014 - Dec 10, 2014
#6	-4.10% Oct 3, 2016 - Oct 5, 2016	-46.67% May 21, 2012 - Sep 7, 2012
#7	-1.45% Sep 7, 2016 - Sep 9, 2016	-35.00% Dec 2, 2013 - Dec 9, 2013
#8	-1.09% Sep 21, 2016 - Sep 23, 2016	-31.67% May 4, 2015 - Nov 3, 2015
#9	-1.07% Aug 30, 2016 - Sep 1, 2016	-31.25% Jan 13, 2015 - Apr 28, 2015
#10	-0.67% Sep 2, 2016 - Sep 7, 2016	-20.00% Sep 13, 2012 - Sep 18, 2012
#11	N/A	-18.52% Dec 11, 2014 - Dec 16, 2014
#12	N/A	-11.76% Sep 7, 2012 - Sep 12, 2012
#13	N/A	-10.00% Nov 21, 2013 - Dec 2, 2013
#14	N/A	-10.00% Dec 18, 2014 - Dec 22, 2014
#15	N/A	-10.00% Jan 6, 2015 - Jan 13, 2015