BCYC vs RNLX

Comparison between Bicycle Therapeutics Plc (BCYC, Company) and Renalytix Plc (RNLX, Company).

5-Year PerformanceBCYC has outperformed RNLX, delivering a return of -35.7% compared to -72.5%

BCYC vs RNLX - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	BCYC(COMPANY)	RNLX(COMPANY)
Market Cap	$293M	$295M
Max Drawdown	93.67%	99.87%
Sharpe Ratio	-1.41	-2.14
5Y Beta	1.27	N/A
Industry	Biotechnology	N/A
P/E Ratio	-1.33	-10.08
PEG Ratio	-0.18	N/A
5Y EPS CAGR	11.06%	N/A
Debt to Equity	0.00%	171.49%
Free Cash Flow Yield	-78.95%	-8.30%
P/S Ratio	4.55	125.29
P/B Ratio	0.52	-26.03

Market Cap

BCYC

$293M

Winner

RNLX

$295M

Max Drawdown

Winner

BCYC

93.67%

RNLX

99.87%

Sharpe Ratio

Winner

BCYC

-1.41

RNLX

-2.14

5Y Beta

BCYC

1.27

RNLX

N/A

Industry

BCYC

Biotechnology

RNLX

N/A

P/E Ratio

BCYC

-1.33

Winner

RNLX

-10.08

PEG Ratio

BCYC

-0.18

RNLX

N/A

5Y EPS CAGR

BCYC

11.06%

RNLX

N/A

Debt to Equity

Winner

BCYC

0.00%

RNLX

171.49%

Free Cash Flow Yield

BCYC

-78.95%

Winner

RNLX

-8.30%

P/S Ratio

Winner

BCYC

4.55

RNLX

125.29

P/B Ratio

BCYC

0.52

Winner

RNLX

-26.03

BCYC vs RNLX - Historical Returns

Returns include dividend reinvestment.

Period	BCYC	RNLX
1 month	-2.27%	+0.78%
3 months	-20.04%	-51.69%
6 months	-44.32%	-66.49%
1 year	-55.00%	N/A
5 years(CAGR)	-35.73%	-72.53%
Max(CAGR)	-14.60%	-61.31%

BCYC

-2.27%

Winner

RNLX

+0.78%

Winner

BCYC

-20.04%

RNLX

-51.69%

Winner

BCYC

-44.32%

RNLX

-66.49%

BCYC

-55.00%

RNLX

N/A

5Y(CAGR)

Winner

BCYC

-35.73%

RNLX

-72.53%

Max(CAGR)

Winner

BCYC

-14.60%

RNLX

-61.31%

BCYC vs RNLX - Annual Returns (2019 - 2026)

Returns include dividend reinvestment.

Year	BCYC	RNLX
2026	-42.07%	-67.67%
2025	-50.70%	-5.97%
2024	-24.08%	-51.27%
2023	-39.73%	-79.79%
2022	-50.25%	-87.95%
2021	+217.03%	-3.05%
2020	+82.79%	+18.52%
2019	-21.42%	N/A

BCYC vs RNLX Drawdown Comparison

The maximum drawdown for BCYC was -93.67%, occurring on Jul 24, 2026. This drawdown has not yet recovered.

The maximum drawdown for RNLX was -99.87%, occurring on Apr 24, 2026. This drawdown has not yet recovered.

The current BCYC drawdown is -93.67%. The current RNLX drawdown is -99.85%.

Rank	BCYC	RNLX
#1	-93.67% Nov 15, 2021 - Jul 24, 2026	-99.87% Jul 28, 2021 - Apr 24, 2026
#2	-53.96% Jun 19, 2019 - Feb 14, 2020	-41.16% Aug 5, 2020 - Jan 5, 2021
#3	-41.61% Mar 10, 2020 - May 28, 2020	-24.32% Mar 15, 2021 - Apr 23, 2021
#4	-25.95% Feb 5, 2021 - Apr 1, 2021	-22.28% Jun 1, 2021 - Jul 28, 2021
#5	-20.84% Jul 23, 2021 - Aug 30, 2021	-18.69% Jan 25, 2021 - Mar 8, 2021
#6	-18.83% Feb 26, 2020 - Mar 4, 2020	-15.31% Apr 26, 2021 - May 24, 2021
#7	-18.70% Jul 15, 2020 - Sep 16, 2020	-13.01% Jan 5, 2021 - Jan 13, 2021
#8	-16.36% Apr 8, 2021 - Jul 13, 2021	-7.42% May 24, 2021 - Jun 1, 2021
#9	-15.98% Jun 8, 2020 - Jul 14, 2020	-5.32% Jul 23, 2020 - Jul 27, 2020
#10	-15.96% Nov 30, 2020 - Jan 14, 2021	-3.47% Jul 29, 2020 - Aug 3, 2020
#11	-15.70% Mar 4, 2020 - Mar 10, 2020	-1.93% Mar 9, 2021 - Mar 11, 2021
#12	-14.32% Jan 19, 2021 - Feb 5, 2021	-0.39% Jul 27, 2020 - Jul 29, 2020
#13	-14.18% May 24, 2019 - Jun 14, 2019	-0.31% Aug 3, 2020 - Aug 5, 2020
#14	-13.83% Oct 14, 2021 - Nov 15, 2021	N/A
#15	-12.02% Sep 21, 2020 - Nov 17, 2020	N/A