BCYC vs ATLO

Comparison between Bicycle Therapeutics Plc (BCYC, Company) and Ames National Corp (ATLO, Company).

BCYC is from the Healthcare sector, while ATLO is from the Financial Services sector.

5-Year PerformanceATLO has outperformed BCYC, delivering a return of +10.8% compared to -32.5%

BCYC vs ATLO - Performance Comparison

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Key Characteristics

Financial metrics and valuation ratios

Metric	BCYC(COMPANY)	ATLO(COMPANY)
Market Cap	$277M	$277M
Max Drawdown	93.69%	66.71%
Sharpe Ratio	-1.01	2.66
5Y Beta	1.27	0.47
Industry	Biotechnology	Banks - Regional
P/E Ratio	-1.45	12.90
Forward P/E	N/A	12.76
PEG Ratio	N/A	0.14
Dividend Yield	N/A	2.84%
5Y Dividends CAGR	N/A	-2.72%
5Y EPS CAGR	7.36%	0.77%
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	-75.15%	7.83%
P/S Ratio	4.54	3.87
P/B Ratio	0.53	1.27

Market Cap

BCYC

$277M

Winner

ATLO

$277M

Max Drawdown

BCYC

93.69%

Winner

ATLO

66.71%

Sharpe Ratio

BCYC

-1.01

Winner

ATLO

2.66

5Y Beta

BCYC

1.27

Winner

ATLO

0.47

Industry

BCYC

Biotechnology

ATLO

Banks - Regional

P/E Ratio

Winner

BCYC

-1.45

ATLO

12.90

Forward P/E

BCYC

N/A

ATLO

12.76

PEG Ratio

BCYC

N/A

ATLO

0.14

Dividend Yield

BCYC

N/A

ATLO

2.84%

5Y Dividends CAGR

BCYC

N/A

ATLO

-2.72%

5Y EPS CAGR

Winner

BCYC

7.36%

ATLO

0.77%

Debt to Equity

BCYC

0.00%

ATLO

0.00%

Free Cash Flow Yield

BCYC

-75.15%

Winner

ATLO

7.83%

P/S Ratio

BCYC

4.54

Winner

ATLO

3.87

P/B Ratio

Winner

BCYC

0.53

ATLO

1.27

BCYC vs ATLO - Historical Returns

Returns include dividend reinvestment.

Period	BCYC	ATLO
1 month	-6.67%	+8.53%
3 months	-13.98%	+14.59%
6 months	-24.25%	+18.02%
1 year	-43.77%	+71.15%
5 years(CAGR)	-32.48%	+10.78%
10 years(CAGR)	N/A	+5.92%
Max(CAGR)	-13.93%	+6.28%

BCYC

-6.67%

Winner

ATLO

+8.53%

BCYC

-13.98%

Winner

ATLO

+14.59%

BCYC

-24.25%

Winner

ATLO

+18.02%

BCYC

-43.77%

Winner

ATLO

+71.15%

5Y(CAGR)

BCYC

-32.48%

Winner

ATLO

+10.78%

10Y(CAGR)

BCYC

N/A

ATLO

+5.92%

Max(CAGR)

BCYC

-13.93%

Winner

ATLO

+6.28%

BCYC vs ATLO - Annual Returns (2000 - 2026)

Returns include dividend reinvestment.

Year	BCYC	ATLO
2026	-39.22%	+41.69%
2025	-50.70%	+46.03%
2024	-24.08%	-18.79%
2023	-39.73%	-3.09%
2022	-50.25%	+1.76%
2021	+217.03%	+9.64%
2020	+82.79%	-9.42%
2019	-21.42%	+11.85%
2018	N/A	-6.63%
2017	N/A	-13.33%
2016	N/A	+46.16%
2015	N/A	-1.61%
2014	N/A	+20.29%
2013	N/A	+2.94%
2012	N/A	+14.47%
2011	N/A	-7.89%
2010	N/A	+4.89%
2009	N/A	-19.84%
2008	N/A	+46.71%
2007	N/A	-2.25%
2006	N/A	-15.44%
2005	N/A	-3.93%
2004	N/A	+43.31%
2003	N/A	+30.91%
2002	N/A	+21.65%
2001	N/A	-24.12%
2000	N/A	+8.86%

BCYC vs ATLO Drawdown Comparison

The maximum drawdown for BCYC was -93.69%, occurring on Jul 29, 2026. This drawdown has not yet recovered.

The maximum drawdown for ATLO was -63.72%, occurring on Mar 9, 2009. Recovery took 2071 trading sessions.

The current BCYC drawdown is -93.36%.

Rank	BCYC	ATLO
#1	-93.69% Nov 15, 2021 - Jul 29, 2026	-63.72% Sep 18, 2008 - Dec 8, 2016
#2	-53.96% Jun 19, 2019 - Feb 14, 2020	-57.26% Jul 20, 2005 - Sep 18, 2008
#3	-41.61% Mar 10, 2020 - May 28, 2020	-54.69% Mar 26, 2001 - Sep 8, 2004
#4	-25.95% Feb 5, 2021 - Apr 1, 2021	-45.46% Dec 9, 2016 - Dec 11, 2025
#5	-20.84% Jul 23, 2021 - Aug 30, 2021	-27.27% Dec 29, 2000 - Mar 26, 2001
#6	-18.83% Feb 26, 2020 - Mar 4, 2020	-23.33% Dec 2, 2004 - Jun 6, 2005
#7	-18.70% Jul 15, 2020 - Sep 16, 2020	-9.33% Jun 13, 2005 - Jul 20, 2005
#8	-16.36% Apr 8, 2021 - Jul 13, 2021	-7.09% Apr 9, 2026 - Jun 5, 2026
#9	-15.98% Jun 8, 2020 - Jul 14, 2020	-6.52% Jun 23, 2026 - Aug 3, 2026
#10	-15.96% Nov 30, 2020 - Jan 14, 2021	-5.77% Feb 15, 2000 - Apr 3, 2000
#11	-15.70% Mar 4, 2020 - Mar 10, 2020	-5.17% Feb 17, 2026 - Mar 30, 2026
#12	-14.32% Jan 19, 2021 - Feb 5, 2021	-4.77% Dec 12, 2025 - Jan 21, 2026
#13	-14.18% May 24, 2019 - Jun 14, 2019	-3.06% Jun 12, 2026 - Jun 23, 2026
#14	-13.83% Oct 14, 2021 - Nov 15, 2021	-2.33% Feb 6, 2026 - Feb 17, 2026
#15	-12.02% Sep 21, 2020 - Nov 17, 2020	-2.10% Sep 14, 2004 - Oct 26, 2004