AYTU vs PIRS

Comparison between Aytu BioPharma Inc (AYTU, Company) and Pieris Pharmaceuticals Inc (PIRS, Company).

5-Year PerformancePIRS has outperformed AYTU, delivering a return of -44.7% compared to -54.0%

AYTU vs PIRS - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	AYTU(COMPANY)	PIRS(COMPANY)
Market Cap	$24M	$24M
Max Drawdown	100.00%	99.14%
Sharpe Ratio	0.40	0.55
5Y Beta	0.00	N/A
Industry	Drug Manufacturers - Specialty & Generic	N/A
P/E Ratio	-0.64	0.98
Forward P/E	26.88	N/A
PEG Ratio	0.00	N/A
5Y EPS CAGR	-32.17%	N/A
Debt to Equity	32.46%	0.00%
Free Cash Flow Yield	5.96%	62.31%
P/S Ratio	0.42	1.47
P/B Ratio	0.70	1.48

Market Cap

AYTU

$24M

Winner

PIRS

$24M

Max Drawdown

AYTU

100.00%

Winner

PIRS

99.14%

Sharpe Ratio

AYTU

0.40

Winner

PIRS

0.55

5Y Beta

AYTU

0.00

PIRS

N/A

Industry

AYTU

Drug Manufacturers - Specialty & Generic

PIRS

N/A

P/E Ratio

Winner

AYTU

-0.64

PIRS

0.98

Forward P/E

AYTU

26.88

PIRS

N/A

PEG Ratio

AYTU

0.00

PIRS

N/A

5Y EPS CAGR

AYTU

-32.17%

PIRS

N/A

Debt to Equity

AYTU

32.46%

Winner

PIRS

0.00%

Free Cash Flow Yield

AYTU

5.96%

Winner

PIRS

62.31%

P/S Ratio

Winner

AYTU

0.42

PIRS

1.47

P/B Ratio

Winner

AYTU

0.70

PIRS

1.48

AYTU vs PIRS - Historical Returns

Returns include dividend reinvestment.

Period	AYTU	PIRS
1 month	-5.02%	-15.53%
3 months	-21.21%	-18.42%
6 months	-14.05%	+36.00%
1 year	+5.05%	+21.43%
5 years(CAGR)	-54.04%	-44.70%
10 years(CAGR)	-67.59%	-27.18%
Max(CAGR)	-67.59%	-27.18%

Winner

AYTU

-5.02%

PIRS

-15.53%

AYTU

-21.21%

Winner

PIRS

-18.42%

AYTU

-14.05%

Winner

PIRS

+36.00%

AYTU

+5.05%

Winner

PIRS

+21.43%

5Y(CAGR)

AYTU

-54.04%

Winner

PIRS

-44.70%

10Y(CAGR)

AYTU

-67.59%

Winner

PIRS

-27.18%

Max(CAGR)

AYTU

-67.59%

Winner

PIRS

-27.18%

AYTU vs PIRS - Annual Returns (2015 - 2026)

Returns include dividend reinvestment.

Year	AYTU	PIRS
2026	-24.91%	N/A
2025	+52.76%	N/A
2024	-41.18%	-8.70%
2023	-28.03%	-83.30%
2022	-87.81%	-73.40%
2021	-78.33%	+38.46%
2020	-42.50%	-26.90%
2019	+21.23%	+23.97%
2018	-98.28%	-65.68%
2017	-88.85%	+417.12%
2016	N/A	-38.64%
2015	N/A	-37.26%

AYTU vs PIRS Drawdown Comparison

The maximum drawdown for AYTU was -100.00%, occurring on Apr 7, 2025. This drawdown has not yet recovered.

The maximum drawdown for PIRS was -99.14%, occurring on Jul 11, 2024. This drawdown has not yet recovered.

The current AYTU drawdown is -100.00%. The current PIRS drawdown is -98.20%.

Rank	AYTU	PIRS
#1	-100.00% Feb 8, 2017 - Apr 7, 2025	-99.14% Feb 13, 2018 - Jul 11, 2024
#2	-11.00% Feb 1, 2017 - Feb 8, 2017	-67.74% Jun 23, 2015 - May 25, 2017
#3	N/A	-29.33% Apr 15, 2015 - Jun 19, 2015
#4	N/A	-28.33% Oct 5, 2017 - Dec 26, 2017
#5	N/A	-24.05% Jul 11, 2017 - Oct 2, 2017
#6	N/A	-14.31% Jun 2, 2017 - Jun 29, 2017
#7	N/A	-11.40% Feb 2, 2018 - Feb 9, 2018
#8	N/A	-10.71% Jan 2, 2018 - Jan 26, 2018
#9	N/A	-5.04% Jan 26, 2018 - Feb 2, 2018
#10	N/A	-4.11% Apr 13, 2015 - Apr 15, 2015
#11	N/A	-3.15% May 25, 2017 - May 30, 2017
#12	N/A	-1.50% Dec 26, 2017 - Dec 28, 2017
#13	N/A	-0.87% May 30, 2017 - Jun 1, 2017
#14	N/A	-0.32% Oct 2, 2017 - Oct 4, 2017