AXGN vs TRVI

Comparison between Axogen Inc (AXGN, Company) and Trevi Therapeutics Inc (TRVI, Company).

Both AXGN and TRVI are from the Healthcare sector.

5-Year PerformanceTRVI has outperformed AXGN, delivering a return of +52.6% compared to +15.3%

AXGN vs TRVI - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	AXGN(COMPANY)	TRVI(COMPANY)
Market Cap	$2.26B	$2.25B
Max Drawdown	95.37%	95.45%
Sharpe Ratio	2.94	2.16
5Y Beta	0.87	0.63
Industry	Medical Devices	Biotechnology
P/E Ratio	-68.67	-48.58
Forward P/E	384.62	N/A
PEG Ratio	-0.24	N/A
5Y EPS CAGR	2.38%	-27.09%
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	0.41%	-2.02%
P/S Ratio	9.50	N/A
P/B Ratio	9.25	14.45

Market Cap

Winner

AXGN

$2.26B

TRVI

$2.25B

Max Drawdown

Winner

AXGN

95.37%

TRVI

95.45%

Sharpe Ratio

Winner

AXGN

2.94

TRVI

2.16

5Y Beta

AXGN

0.87

Winner

TRVI

0.63

Industry

AXGN

Medical Devices

TRVI

Biotechnology

P/E Ratio

Winner

AXGN

-68.67

TRVI

-48.58

Forward P/E

AXGN

384.62

TRVI

N/A

PEG Ratio

AXGN

-0.24

TRVI

N/A

5Y EPS CAGR

Winner

AXGN

2.38%

TRVI

-27.09%

Debt to Equity

AXGN

0.00%

TRVI

0.00%

Free Cash Flow Yield

Winner

AXGN

0.41%

TRVI

-2.02%

P/S Ratio

AXGN

9.50

TRVI

N/A

P/B Ratio

Winner

AXGN

9.25

TRVI

14.45

AXGN vs TRVI - Historical Returns

Returns include dividend reinvestment.

Period	AXGN	TRVI
1 month	+8.40%	+26.22%
3 months	+39.32%	+53.81%
6 months	+36.98%	+41.25%
1 year	+329.13%	+220.67%
5 years(CAGR)	+15.26%	+52.62%
10 years(CAGR)	+21.83%	N/A
Max(CAGR)	+12.73%	+12.38%

AXGN

+8.40%

Winner

TRVI

+26.22%

AXGN

+39.32%

Winner

TRVI

+53.81%

AXGN

+36.98%

Winner

TRVI

+41.25%

Winner

AXGN

+329.13%

TRVI

+220.67%

5Y(CAGR)

AXGN

+15.26%

Winner

TRVI

+52.62%

10Y(CAGR)

AXGN

+21.83%

TRVI

N/A

Max(CAGR)

Winner

AXGN

+12.73%

TRVI

+12.38%

AXGN vs TRVI - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	AXGN	TRVI
2026	+44.94%	+52.65%
2025	+99.57%	+187.16%
2024	+138.49%	+216.92%
2023	-30.87%	-33.99%
2022	+0.00%	+144.30%
2021	-46.49%	-70.48%
2020	+3.23%	-35.47%
2019	-13.28%	-52.47%
2018	-26.91%	N/A
2017	+217.98%	N/A
2016	+78.22%	N/A
2015	+38.89%	N/A
2014	-25.36%	N/A
2013	+63.27%	N/A
2012	+3.85%	N/A
2011	-32.50%	N/A
2010	+2.78%	N/A
2009	+46.18%	N/A
2008	+111.54%	N/A
2007	+52.94%	N/A
2006	+27.45%	N/A
2005	-65.11%	N/A
2004	+114.29%	N/A
2003	+65.31%	N/A
2002	-68.71%	N/A
2001	-30.85%	N/A
2000	+25.00%	N/A
1999	-29.74%	N/A

AXGN vs TRVI Drawdown Comparison

The maximum drawdown for AXGN was -95.37%, occurring on Aug 16, 2002. Recovery took 1825 trading sessions.

The maximum drawdown for TRVI was -95.45%, occurring on Feb 23, 2022. Recovery took 1601 trading sessions.

The current AXGN drawdown is -19.62%.

Rank	AXGN	TRVI
#1	-95.37% Mar 27, 2000 - Jul 2, 2007	-95.45% Jun 3, 2019 - Oct 14, 2025
#2	-93.54% Jul 23, 2018 - Nov 1, 2023	-29.50% Dec 10, 2025 - Apr 15, 2026
#3	-82.67% Jul 5, 2007 - Jun 21, 2016	-14.03% Apr 20, 2026 - Jun 17, 2026
#4	-49.98% Nov 9, 1999 - Jan 14, 2000	-11.98% Nov 11, 2025 - Nov 26, 2025
#5	-36.67% Jan 14, 2000 - Mar 24, 2000	-8.75% Oct 31, 2025 - Nov 10, 2025
#6	-21.42% Jan 5, 2018 - Feb 27, 2018	-5.26% Dec 3, 2025 - Dec 10, 2025
#7	-17.43% Jul 11, 2016 - Aug 4, 2016	-4.10% May 21, 2019 - May 30, 2019
#8	-16.67% Sep 8, 2016 - Jan 9, 2017	-3.58% Oct 22, 2025 - Oct 30, 2025
#9	-13.57% Jul 21, 2017 - Aug 29, 2017	-3.51% May 10, 2019 - May 14, 2019
#10	-11.10% Nov 4, 1999 - Nov 9, 1999	-3.37% May 14, 2019 - May 20, 2019
#11	-11.01% Jan 31, 2017 - Apr 12, 2017	-2.54% Oct 16, 2025 - Oct 20, 2025
#12	-10.19% Mar 26, 2018 - Apr 18, 2018	-1.86% Jun 22, 2026 - Jun 25, 2026
#13	-9.78% Nov 10, 2017 - Nov 21, 2017	-1.58% May 8, 2019 - May 10, 2019
#14	-8.20% May 1, 2017 - May 12, 2017	-0.75% Nov 26, 2025 - Dec 1, 2025
#15	-7.57% Jun 8, 2017 - Jun 30, 2017	-0.37% Oct 20, 2025 - Oct 22, 2025