AVTX vs CCCC

Comparison between Avalo Therapeutics Inc (AVTX, Company) and C4 Therapeutics Inc (CCCC, Company).

Both AVTX and CCCC are from the Healthcare sector.

5-Year PerformanceCCCC has outperformed AVTX, delivering a return of -37.9% compared to -72.8%

AVTX vs CCCC - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	AVTX(COMPANY)	CCCC(COMPANY)
Market Cap	$404M	$403M
Max Drawdown	99.98%	97.82%
Sharpe Ratio	1.55	1.34
5Y Beta	0.56	1.80
Industry	Biotechnology	Biotechnology
P/E Ratio	-3.90	-3.09
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	-12.74%	-23.85%
P/S Ratio	9875.25	11.61
P/B Ratio	3.78	1.69

Market Cap

Winner

AVTX

$404M

CCCC

$403M

Max Drawdown

AVTX

99.98%

Winner

CCCC

97.82%

Sharpe Ratio

Winner

AVTX

1.55

CCCC

1.34

5Y Beta

Winner

AVTX

0.56

CCCC

1.80

Industry

AVTX

Biotechnology

CCCC

Biotechnology

P/E Ratio

Winner

AVTX

-3.90

CCCC

-3.09

Debt to Equity

AVTX

0.00%

CCCC

0.00%

Free Cash Flow Yield

Winner

AVTX

-12.74%

CCCC

-23.85%

P/S Ratio

AVTX

9875.25

Winner

CCCC

11.61

P/B Ratio

AVTX

3.78

Winner

CCCC

1.69

AVTX vs CCCC - Historical Returns

Returns include dividend reinvestment.

Period	AVTX	CCCC
1 month	-25.98%	+23.03%
3 months	-11.67%	+41.82%
6 months	-20.65%	+57.89%
1 year	+202.46%	+140.74%
5 years(CAGR)	-72.81%	-37.87%
10 years(CAGR)	-45.52%	N/A
Max(CAGR)	-46.72%	-28.09%

AVTX

-25.98%

Winner

CCCC

+23.03%

AVTX

-11.67%

Winner

CCCC

+41.82%

AVTX

-20.65%

Winner

CCCC

+57.89%

Winner

AVTX

+202.46%

CCCC

+140.74%

5Y(CAGR)

AVTX

-72.81%

Winner

CCCC

-37.87%

10Y(CAGR)

AVTX

-45.52%

CCCC

N/A

Max(CAGR)

AVTX

-46.72%

Winner

CCCC

-28.09%

AVTX vs CCCC - Annual Returns (2015 - 2026)

Returns include dividend reinvestment.

Year	AVTX	CCCC
2026	-13.28%	+102.07%
2025	+115.42%	-47.81%
2024	-14.70%	-44.79%
2023	-99.24%	-11.44%
2022	-76.80%	-82.24%
2021	-35.61%	+0.75%
2020	-47.51%	+29.97%
2019	+54.44%	N/A
2018	-3.00%	N/A
2017	+259.51%	N/A
2016	-77.13%	N/A
2015	-16.25%	N/A

AVTX vs CCCC Drawdown Comparison

The maximum drawdown for AVTX was -99.98%, occurring on May 28, 2025. This drawdown has not yet recovered.

The maximum drawdown for CCCC was -97.82%, occurring on Apr 16, 2025. This drawdown has not yet recovered.

The current AVTX drawdown is -99.93%. The current CCCC drawdown is -92.28%.

Rank	AVTX	CCCC
#1	-99.98% Feb 27, 2019 - May 28, 2025	-97.82% Sep 23, 2021 - Apr 16, 2025
#2	-91.55% Nov 23, 2016 - Mar 7, 2018	-34.65% Feb 10, 2021 - Sep 7, 2021
#3	-60.57% Mar 17, 2016 - Nov 18, 2016	-19.07% Nov 27, 2020 - Dec 23, 2020
#4	-46.64% Mar 7, 2018 - Feb 25, 2019	-15.43% Oct 6, 2020 - Oct 20, 2020
#5	-35.56% Nov 16, 2015 - Mar 16, 2016	-13.74% Dec 23, 2020 - Jan 11, 2021
#6	N/A	-13.38% Jan 25, 2021 - Feb 2, 2021
#7	N/A	-9.71% Oct 21, 2020 - Nov 16, 2020
#8	N/A	-6.78% Jan 13, 2021 - Jan 22, 2021
#9	N/A	-2.80% Jan 11, 2021 - Jan 13, 2021
#10	N/A	-2.56% Sep 17, 2021 - Sep 21, 2021
#11	N/A	-2.54% Feb 2, 2021 - Feb 5, 2021
#12	N/A	-2.44% Feb 5, 2021 - Feb 10, 2021
#13	N/A	-1.93% Sep 13, 2021 - Sep 17, 2021
#14	N/A	-1.83% Nov 17, 2020 - Nov 24, 2020
#15	N/A	-0.93% Sep 7, 2021 - Sep 9, 2021