ARVN vs NGNE

Comparison between Arvinas Inc (ARVN, Company) and Neoleukin Therapeutics Inc (NGNE, Company).

Both ARVN and NGNE are from the Healthcare sector.

5-Year PerformanceNGNE has outperformed ARVN, delivering a return of -31.1% compared to -37.3%

ARVN vs NGNE - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	ARVN(COMPANY)	NGNE(COMPANY)
Market Cap	$495M	$492M
Max Drawdown	94.37%	98.34%
Sharpe Ratio	0.26	1.00
5Y Beta	1.14	1.88
Industry	Biotechnology	Biotechnology
P/E Ratio	-2.33	-4.82
Forward P/E	17.86	N/A
PEG Ratio	-0.01	-0.38
5Y EPS CAGR	1.07%	11.24%
Debt to Equity	0.13%	0.00%
Free Cash Flow Yield	-51.93%	-16.90%

Market Cap

Winner

ARVN

$495M

NGNE

$492M

Max Drawdown

Winner

ARVN

94.37%

NGNE

98.34%

Sharpe Ratio

ARVN

0.26

Winner

NGNE

1.00

5Y Beta

Winner

ARVN

1.14

NGNE

1.88

Industry

ARVN

Biotechnology

NGNE

Biotechnology

P/E Ratio

ARVN

-2.33

Winner

NGNE

-4.82

Forward P/E

ARVN

17.86

NGNE

N/A

PEG Ratio

ARVN

-0.01

Winner

NGNE

-0.38

5Y EPS CAGR

ARVN

1.07%

Winner

NGNE

11.24%

Debt to Equity

ARVN

0.13%

Winner

NGNE

0.00%

Free Cash Flow Yield

ARVN

-51.93%

Winner

NGNE

-16.90%

ARVN vs NGNE - Historical Returns

Returns include dividend reinvestment.

Period	ARVN	NGNE
1 month	-12.64%	+12.69%
3 months	-29.57%	+61.69%
6 months	-32.00%	+63.54%
1 year	+2.68%	+72.30%
5 years(CAGR)	-37.31%	-31.10%
10 years(CAGR)	N/A	-13.19%
Max(CAGR)	-9.12%	-15.20%

ARVN

-12.64%

Winner

NGNE

+12.69%

ARVN

-29.57%

Winner

NGNE

+61.69%

ARVN

-32.00%

Winner

NGNE

+63.54%

ARVN

+2.68%

Winner

NGNE

+72.30%

5Y(CAGR)

ARVN

-37.31%

Winner

NGNE

-31.10%

10Y(CAGR)

ARVN

N/A

NGNE

-13.19%

Max(CAGR)

Winner

ARVN

-9.12%

NGNE

-15.20%

ARVN vs NGNE - Annual Returns (2014 - 2026)

Returns include dividend reinvestment.

Year	ARVN	NGNE
2026	-33.13%	+56.40%
2025	-37.22%	-10.00%
2024	-53.81%	+15.05%
2023	+23.38%	+91.88%
2022	-58.06%	-90.27%
2021	-2.03%	-65.89%
2020	+104.95%	+18.99%
2019	+197.54%	+428.76%
2018	-19.94%	-82.00%
2017	N/A	-27.41%
2016	N/A	+33.90%
2015	N/A	+63.56%
2014	N/A	-37.24%

ARVN vs NGNE Drawdown Comparison

The maximum drawdown for ARVN was -94.37%, occurring on May 14, 2025. This drawdown has not yet recovered.

The maximum drawdown for NGNE was -98.34%, occurring on Apr 8, 2025. This drawdown has not yet recovered.

The current ARVN drawdown is -92.89%. The current NGNE drawdown is -92.88%.

Rank	ARVN	NGNE
#1	-94.37% Jul 29, 2021 - May 14, 2025	-98.34% Aug 14, 2015 - Apr 8, 2025
#2	-64.42% May 11, 2020 - Dec 14, 2020	-89.57% Mar 12, 2014 - Aug 10, 2015
#3	-44.26% Jul 26, 2019 - Nov 13, 2019	-16.18% Aug 11, 2015 - Aug 14, 2015
#4	-39.71% Nov 7, 2018 - Feb 4, 2019	N/A
#5	-39.45% Feb 6, 2020 - May 7, 2020	N/A
#6	-37.96% Feb 15, 2019 - Jun 27, 2019	N/A
#7	-36.31% Jan 19, 2021 - Jul 23, 2021	N/A
#8	-18.79% Sep 28, 2018 - Oct 29, 2018	N/A
#9	-11.42% Jul 5, 2019 - Jul 26, 2019	N/A
#10	-10.51% Dec 15, 2020 - Dec 22, 2020	N/A
#11	-7.97% Dec 12, 2019 - Dec 26, 2019	N/A
#12	-7.61% Jun 27, 2019 - Jul 3, 2019	N/A
#13	-7.41% Dec 26, 2019 - Jan 10, 2020	N/A
#14	-6.10% Jan 15, 2020 - Feb 5, 2020	N/A
#15	-6.05% Feb 4, 2019 - Feb 8, 2019	N/A