ANVS vs TIL

Comparison between Annovis Bio Inc (ANVS, Company) and Instil Bio Inc (TIL, Company).

Both ANVS and TIL are from the Healthcare sector.

5-Year PerformanceTIL has outperformed ANVS, delivering a return of -54.9% compared to -56.5%

ANVS vs TIL - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	ANVS(COMPANY)	TIL(COMPANY)
Market Cap	$52M	$52M
Max Drawdown	98.99%	98.83%
Sharpe Ratio	-0.05	-1.14
5Y Beta	1.59	1.97
Industry	Biotechnology	Biotechnology
P/E Ratio	-1.09	-1.09
5Y EPS CAGR	6.84%	N/A
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	-51.37%	-65.33%
P/S Ratio	N/A	54248.82
P/B Ratio	23.95	0.48

Market Cap

ANVS

$52M

Winner

TIL

$52M

Max Drawdown

ANVS

98.99%

Winner

TIL

98.83%

Sharpe Ratio

Winner

ANVS

-0.05

TIL

-1.14

5Y Beta

Winner

ANVS

1.59

TIL

1.97

Industry

ANVS

Biotechnology

TIL

Biotechnology

P/E Ratio

Winner

ANVS

-1.09

TIL

-1.09

5Y EPS CAGR

ANVS

6.84%

TIL

N/A

Debt to Equity

ANVS

0.00%

TIL

0.00%

Free Cash Flow Yield

Winner

ANVS

-51.37%

TIL

-65.33%

P/S Ratio

ANVS

N/A

TIL

54248.82

P/B Ratio

ANVS

23.95

Winner

TIL

0.48

ANVS vs TIL - Historical Returns

Returns include dividend reinvestment.

Period	ANVS	TIL
1 month	-1.98%	-4.10%
3 months	-6.72%	-12.86%
6 months	-39.76%	+2.40%
1 year	-31.42%	-73.75%
5 years(CAGR)	-56.47%	-54.94%
Max(CAGR)	-23.21%	-55.22%

Winner

ANVS

-1.98%

TIL

-4.10%

Winner

ANVS

-6.72%

TIL

-12.86%

ANVS

-39.76%

Winner

TIL

+2.40%

Winner

ANVS

-31.42%

TIL

-73.75%

5Y(CAGR)

ANVS

-56.47%

Winner

TIL

-54.94%

Max(CAGR)

Winner

ANVS

-23.21%

TIL

-55.22%

ANVS vs TIL - Annual Returns (2020 - 2026)

Returns include dividend reinvestment.

Year	ANVS	TIL
2026	-52.47%	-35.67%
2025	-32.29%	-49.12%
2024	-73.43%	+145.69%
2023	+43.96%	-36.50%
2022	-32.10%	-96.52%
2021	+115.71%	-35.29%
2020	-21.38%	N/A

ANVS vs TIL Drawdown Comparison

The maximum drawdown for ANVS was -98.99%, occurring on Apr 8, 2025. This drawdown has not yet recovered.

The maximum drawdown for TIL was -98.83%, occurring on Dec 7, 2023. This drawdown has not yet recovered.

The current ANVS drawdown is -98.57%. The current TIL drawdown is -98.66%.

Rank	ANVS	TIL
#1	-98.99% Jul 13, 2021 - Apr 8, 2025	-98.83% Mar 26, 2021 - Dec 7, 2023
#2	-73.93% Jan 29, 2020 - Jan 13, 2021	-9.59% Mar 22, 2021 - Mar 26, 2021
#3	-43.94% Mar 17, 2021 - May 21, 2021	N/A
#4	-25.67% May 21, 2021 - Jun 3, 2021	N/A
#5	-25.05% Feb 22, 2021 - Mar 15, 2021	N/A
#6	-17.86% Jun 21, 2021 - Jul 2, 2021	N/A
#7	-13.29% Feb 4, 2021 - Feb 9, 2021	N/A
#8	-6.06% Jun 8, 2021 - Jun 10, 2021	N/A
#9	-5.95% Jan 26, 2021 - Feb 2, 2021	N/A
#10	-5.61% Jun 16, 2021 - Jun 21, 2021	N/A
#11	-5.47% Jul 8, 2021 - Jul 12, 2021	N/A
#12	-5.16% Jun 11, 2021 - Jun 16, 2021	N/A
#13	-2.06% Mar 15, 2021 - Mar 17, 2021	N/A
#14	-1.24% Jan 14, 2021 - Jan 21, 2021	N/A
#15	-0.43% Jan 22, 2021 - Jan 26, 2021	N/A