ANNX vs HTLD

Comparison between Annexon Inc (ANNX, Company) and Heartland Express Inc (HTLD, Company).

ANNX is from the Healthcare sector, while HTLD is from the Industrials sector.

5-Year PerformanceHTLD has outperformed ANNX, delivering a return of -1.8% compared to -24.3%

ANNX vs HTLD - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	ANNX(COMPANY)	HTLD(COMPANY)
Market Cap	$1.16B	$1.15B
Max Drawdown	96.06%	74.45%
Sharpe Ratio	1.28	1.27
5Y Beta	1.22	0.80
Industry	Biotechnology	Trucking
P/E Ratio	-4.61	-26.58
Forward P/E	N/A	21.05
PEG Ratio	-0.28	-0.49
Dividend Yield	N/A	0.54%
5Y Dividends CAGR	N/A	4.56%
Debt to Equity	0.00%	20.01%
Free Cash Flow Yield	-15.82%	-5.55%
P/S Ratio	N/A	1.51
P/B Ratio	4.37	1.54

Market Cap

Winner

ANNX

$1.16B

HTLD

$1.15B

Max Drawdown

ANNX

96.06%

Winner

HTLD

74.45%

Sharpe Ratio

Winner

ANNX

1.28

HTLD

1.27

5Y Beta

ANNX

1.22

Winner

HTLD

0.80

Industry

ANNX

Biotechnology

HTLD

Trucking

P/E Ratio

ANNX

-4.61

Winner

HTLD

-26.58

Forward P/E

ANNX

N/A

HTLD

21.05

PEG Ratio

ANNX

-0.28

Winner

HTLD

-0.49

Dividend Yield

ANNX

N/A

HTLD

0.54%

5Y Dividends CAGR

ANNX

N/A

HTLD

4.56%

Debt to Equity

Winner

ANNX

0.00%

HTLD

20.01%

Free Cash Flow Yield

ANNX

-15.82%

Winner

HTLD

-5.55%

P/S Ratio

ANNX

N/A

HTLD

1.51

P/B Ratio

ANNX

4.37

Winner

HTLD

1.54

ANNX vs HTLD - Historical Returns

Returns include dividend reinvestment.

Period	ANNX	HTLD
1 month	+22.88%	-6.08%
3 months	-0.85%	+34.61%
6 months	+10.48%	+41.69%
1 year	+107.14%	+57.51%
5 years(CAGR)	-24.25%	-1.77%
10 years(CAGR)	N/A	-1.13%
Max(CAGR)	-17.12%	+6.93%

Winner

ANNX

+22.88%

HTLD

-6.08%

ANNX

-0.85%

Winner

HTLD

+34.61%

ANNX

+10.48%

Winner

HTLD

+41.69%

Winner

ANNX

+107.14%

HTLD

+57.51%

5Y(CAGR)

ANNX

-24.25%

Winner

HTLD

-1.77%

10Y(CAGR)

ANNX

N/A

HTLD

-1.13%

Max(CAGR)

ANNX

-17.12%

Winner

HTLD

+6.93%

ANNX vs HTLD - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	ANNX	HTLD
2026	+23.67%	+62.29%
2025	-8.73%	-16.87%
2024	+5.99%	-18.90%
2023	-5.22%	-8.04%
2022	-56.70%	-7.91%
2021	-51.94%	-3.23%
2020	+40.93%	-12.78%
2019	N/A	+15.30%
2018	N/A	-22.28%
2017	N/A	+14.22%
2016	N/A	+22.79%
2015	N/A	-36.65%
2014	N/A	+38.28%
2013	N/A	+48.20%
2012	N/A	-1.33%
2011	N/A	-11.81%
2010	N/A	+8.76%
2009	N/A	-3.50%
2008	N/A	+15.56%
2007	N/A	+3.90%
2006	N/A	-2.10%
2005	N/A	-9.94%
2004	N/A	+35.70%
2003	N/A	+6.26%
2002	N/A	+23.72%
2001	N/A	+58.22%
2000	N/A	+49.57%
1999	N/A	+8.62%

ANNX vs HTLD Drawdown Comparison

The maximum drawdown for ANNX was -96.06%, occurring on Apr 10, 2025. This drawdown has not yet recovered.

The maximum drawdown for HTLD was -72.26%, occurring on Nov 20, 2025. This drawdown has not yet recovered.

The current ANNX drawdown is -83.43%. The current HTLD drawdown is -41.69%.

Rank	ANNX	HTLD
#1	-96.06% Mar 16, 2021 - Apr 10, 2025	-72.26% Dec 26, 2014 - Nov 20, 2025
#2	-31.37% Oct 16, 2020 - Dec 23, 2020	-34.55% Aug 14, 2008 - Feb 16, 2011
#3	-27.99% Dec 23, 2020 - Feb 22, 2021	-32.47% Feb 27, 2002 - Jul 15, 2003
#4	-25.64% Aug 12, 2020 - Sep 30, 2020	-28.51% Apr 6, 2011 - Nov 12, 2013
#5	-13.04% Feb 22, 2021 - Mar 11, 2021	-25.37% Apr 20, 2006 - Jul 11, 2007
#6	-10.78% Sep 30, 2020 - Oct 16, 2020	-23.94% Jul 12, 2007 - Jul 22, 2008
#7	-3.12% Aug 3, 2020 - Aug 5, 2020	-22.34% Dec 29, 2004 - Jan 30, 2006
#8	-3.02% Aug 5, 2020 - Aug 10, 2020	-22.27% May 16, 2001 - Jul 17, 2001
#9	-2.83% Jul 29, 2020 - Aug 3, 2020	-22.03% Aug 3, 2001 - Dec 5, 2001
#10	-1.46% Jul 24, 2020 - Jul 28, 2020	-21.22% Sep 4, 2003 - Jun 28, 2004
#11	-0.38% Mar 11, 2021 - Mar 15, 2021	-19.81% Dec 31, 1999 - Apr 7, 2000
#12	N/A	-14.40% Feb 23, 2006 - Apr 19, 2006
#13	N/A	-14.12% May 26, 2000 - Nov 16, 2000
#14	N/A	-12.82% Apr 22, 2014 - Jul 22, 2014
#15	N/A	-12.16% May 1, 2000 - May 26, 2000