ANAB vs TYRA

Comparison between AnaptysBio Inc (ANAB, Company) and Tyra Biosciences Inc (TYRA, Company).

Both ANAB and TYRA are from the Healthcare sector.

5-Year PerformanceANAB has outperformed TYRA, delivering a return of +28.2% compared to +0.8%

ANAB vs TYRA - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	ANAB(COMPANY)	TYRA(COMPANY)
Market Cap	$1.51B	$1.51B
Max Drawdown	92.08%	83.22%
Sharpe Ratio	2.06	1.73
5Y Beta	0.81	1.04
Industry	Biotechnology	Biotechnology
P/E Ratio	-58.95	-10.69
PEG Ratio	0.00	-0.37
5Y EPS CAGR	-4.15%	N/A
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	0.29%	-6.78%
P/S Ratio	6.63	N/A
P/B Ratio	117.87	3.90

Market Cap

Winner

ANAB

$1.51B

TYRA

$1.51B

Max Drawdown

ANAB

92.08%

Winner

TYRA

83.22%

Sharpe Ratio

Winner

ANAB

2.06

TYRA

1.73

5Y Beta

Winner

ANAB

0.81

TYRA

1.04

Industry

ANAB

Biotechnology

TYRA

Biotechnology

P/E Ratio

Winner

ANAB

-58.95

TYRA

-10.69

PEG Ratio

ANAB

0.00

Winner

TYRA

-0.37

5Y EPS CAGR

ANAB

-4.15%

TYRA

N/A

Debt to Equity

ANAB

0.00%

TYRA

0.00%

Free Cash Flow Yield

Winner

ANAB

0.29%

TYRA

-6.78%

P/S Ratio

ANAB

6.63

TYRA

N/A

P/B Ratio

ANAB

117.87

Winner

TYRA

3.90

ANAB vs TYRA - Historical Returns

Returns include dividend reinvestment.

Period	ANAB	TYRA
1 month	-14.50%	-22.60%
3 months	+31.85%	-25.03%
6 months	+87.15%	+19.27%
1 year	+259.27%	+161.28%
5 years(CAGR)	+28.19%	+0.79%
10 years(CAGR)	+18.60%	N/A
Max(CAGR)	+18.60%	+0.79%

Winner

ANAB

-14.50%

TYRA

-22.60%

Winner

ANAB

+31.85%

TYRA

-25.03%

Winner

ANAB

+87.15%

TYRA

+19.27%

Winner

ANAB

+259.27%

TYRA

+161.28%

5Y(CAGR)

Winner

ANAB

+28.19%

TYRA

+0.79%

10Y(CAGR)

ANAB

+18.60%

TYRA

N/A

Max(CAGR)

Winner

ANAB

+18.60%

TYRA

+0.79%

ANAB vs TYRA - Annual Returns (2017 - 2026)

Returns include dividend reinvestment.

Year	ANAB	TYRA
2026	+87.11%	+0.75%
2025	+262.87%	+82.19%
2024	-38.99%	-1.00%
2023	-26.69%	+95.90%
2022	-13.77%	-46.06%
2021	+48.76%	-45.88%
2020	+35.31%	N/A
2019	-74.50%	N/A
2018	-36.58%	N/A
2017	+492.47%	N/A

ANAB vs TYRA Drawdown Comparison

The maximum drawdown for ANAB was -92.08%, occurring on Nov 8, 2019. This drawdown has not yet recovered.

The maximum drawdown for TYRA was -83.22%, occurring on Jun 17, 2022. Recovery took 1058 trading sessions.

The current ANAB drawdown is -34.57%. The current TYRA drawdown is -31.86%.

Rank	ANAB	TYRA
#1	-92.08% Mar 2, 2018 - Nov 8, 2019	-83.22% Nov 4, 2021 - Jan 27, 2026
#2	-32.97% Mar 30, 2017 - Jul 24, 2017	-48.23% Sep 15, 2021 - Nov 3, 2021
#3	-32.31% Jul 24, 2017 - Sep 6, 2017	-35.82% Apr 2, 2026 - Jun 10, 2026
#4	-14.04% Jan 24, 2018 - Feb 14, 2018	-13.45% Jan 29, 2026 - Feb 23, 2026
#5	-10.40% Oct 12, 2017 - Nov 13, 2017	-9.38% Mar 19, 2026 - Mar 31, 2026
#6	-7.89% Feb 24, 2017 - Mar 13, 2017	-5.74% Feb 25, 2026 - Mar 4, 2026
#7	-5.75% Sep 18, 2017 - Oct 5, 2017	-4.31% Mar 4, 2026 - Mar 11, 2026
#8	-5.55% Feb 16, 2018 - Mar 2, 2018	-1.48% Mar 11, 2026 - Mar 16, 2026
#9	-5.19% Jan 27, 2017 - Feb 6, 2017	-1.02% Jan 27, 2026 - Jan 29, 2026
#10	-4.41% Feb 14, 2017 - Feb 17, 2017	-0.05% Mar 31, 2026 - Apr 2, 2026
#11	-4.06% Dec 4, 2017 - Dec 7, 2017	N/A
#12	-3.94% Feb 14, 2018 - Feb 16, 2018	N/A
#13	-3.50% Sep 13, 2017 - Sep 18, 2017	N/A
#14	-3.10% Feb 17, 2017 - Feb 24, 2017	N/A
#15	-2.64% Oct 5, 2017 - Oct 10, 2017	N/A