AMWL vs AKTX

Comparison between American Well Corporation - Class A (AMWL, Company) and Akari Therapeutics Plc (AKTX, Company).

Both AMWL and AKTX are from the Healthcare sector.

5-Year PerformanceAMWL has outperformed AKTX, delivering a return of -49.0% compared to -59.8%

AMWL vs AKTX - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	AMWL(COMPANY)	AKTX(COMPANY)
Market Cap	$148M	$148M
Max Drawdown	99.56%	99.99%
Sharpe Ratio	0.61	0.32
5Y Beta	1.30	0.67
Industry	Health Information Services	Biotechnology
P/E Ratio	-1.65	-8.66
PEG Ratio	N/A	0.00
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	-28.32%	-6.52%
P/S Ratio	0.67	478368.50
P/B Ratio	0.69	1.14

Market Cap

AMWL

$148M

Winner

AKTX

$148M

Max Drawdown

Winner

AMWL

99.56%

AKTX

99.99%

Sharpe Ratio

Winner

AMWL

0.61

AKTX

0.32

5Y Beta

AMWL

1.30

Winner

AKTX

0.67

Industry

AMWL

Health Information Services

AKTX

Biotechnology

P/E Ratio

AMWL

-1.65

Winner

AKTX

-8.66

PEG Ratio

AMWL

N/A

AKTX

0.00

Debt to Equity

AMWL

0.00%

AKTX

0.00%

Free Cash Flow Yield

AMWL

-28.32%

Winner

AKTX

-6.52%

P/S Ratio

Winner

AMWL

0.67

AKTX

478368.50

P/B Ratio

Winner

AMWL

0.69

AKTX

1.14

AMWL vs AKTX - Historical Returns

Returns include dividend reinvestment.

Period	AMWL	AKTX
1 month	+37.11%	+168.15%
3 months	+55.44%	+52.78%
6 months	+117.46%	+11.14%
1 year	+26.01%	-70.61%
5 years(CAGR)	-49.00%	-59.77%
10 years(CAGR)	N/A	-48.61%
Max(CAGR)	-50.07%	-50.01%

AMWL

+37.11%

Winner

AKTX

+168.15%

Winner

AMWL

+55.44%

AKTX

+52.78%

Winner

AMWL

+117.46%

AKTX

+11.14%

Winner

AMWL

+26.01%

AKTX

-70.61%

5Y(CAGR)

Winner

AMWL

-49.00%

AKTX

-59.77%

10Y(CAGR)

AMWL

N/A

AKTX

-48.61%

Max(CAGR)

AMWL

-50.07%

Winner

AKTX

-50.01%

AMWL vs AKTX - Annual Returns (2015 - 2026)

Returns include dividend reinvestment.

Year	AMWL	AKTX
2026	+79.79%	+29.91%
2025	-30.26%	-76.12%
2024	-75.00%	-57.88%
2023	-47.16%	-68.39%
2022	-54.28%	-68.88%
2021	-76.36%	-17.13%
2020	+9.80%	+6.32%
2019	N/A	+5.11%
2018	N/A	-64.24%
2017	N/A	-42.27%
2016	N/A	-48.42%
2015	N/A	-53.97%

AMWL vs AKTX Drawdown Comparison

The maximum drawdown for AMWL was -99.56%, occurring on Nov 20, 2025. This drawdown has not yet recovered.

The maximum drawdown for AKTX was -99.99%, occurring on May 12, 2026. This drawdown has not yet recovered.

The current AMWL drawdown is -98.98%. The current AKTX drawdown is -99.94%.

Rank	AMWL	AKTX
#1	-99.56% Jan 27, 2021 - Nov 20, 2025	-99.99% Sep 21, 2015 - May 12, 2026
#2	-44.09% Oct 7, 2020 - Jan 27, 2021	N/A
#3	-4.28% Sep 30, 2020 - Oct 5, 2020	N/A
#4	-2.74% Sep 23, 2020 - Sep 30, 2020	N/A
#5	-1.17% Sep 17, 2020 - Sep 22, 2020	N/A