AMLX vs EFSC

Comparison between Amylyx Pharmaceuticals Inc (AMLX, Company) and Enterprise Financial Services Corp (EFSC, Company).

AMLX is from the Healthcare sector, while EFSC is from the Financial Services sector.

5-Year PerformanceEFSC has outperformed AMLX, delivering a return of +9.1% compared to +6.6%

AMLX vs EFSC - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	AMLX(COMPANY)	EFSC(COMPANY)
Market Cap	$2.43B	$2.42B
Max Drawdown	96.04%	78.59%
Sharpe Ratio	1.99	0.81
5Y Beta	1.13	0.80
Industry	Drug Manufacturers - Specialty & Generic	Banks - Regional
P/E Ratio	-15.07	12.90
Forward P/E	2.77	12.14
PEG Ratio	N/A	1.23
Dividend Yield	N/A	1.93%
5Y Dividends CAGR	N/A	17.32%
5Y EPS CAGR	N/A	14.04%
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	-4.97%	8.72%
P/S Ratio	0.66	3.48
P/B Ratio	8.27	1.22

Market Cap

Winner

AMLX

$2.43B

EFSC

$2.42B

Max Drawdown

AMLX

96.04%

Winner

EFSC

78.59%

Sharpe Ratio

Winner

AMLX

1.99

EFSC

0.81

5Y Beta

AMLX

1.13

Winner

EFSC

0.80

Industry

AMLX

Drug Manufacturers - Specialty & Generic

EFSC

Banks - Regional

P/E Ratio

Winner

AMLX

-15.07

EFSC

12.90

Forward P/E

Winner

AMLX

2.77

EFSC

12.14

PEG Ratio

AMLX

N/A

EFSC

1.23

Dividend Yield

AMLX

N/A

EFSC

1.93%

5Y Dividends CAGR

AMLX

N/A

EFSC

17.32%

5Y EPS CAGR

AMLX

N/A

EFSC

14.04%

Debt to Equity

AMLX

0.00%

EFSC

0.00%

Free Cash Flow Yield

AMLX

-4.97%

Winner

EFSC

8.72%

P/S Ratio

Winner

AMLX

0.66

EFSC

3.48

P/B Ratio

AMLX

8.27

Winner

EFSC

1.22

AMLX vs EFSC - Historical Returns

Returns include dividend reinvestment.

Period	AMLX	EFSC
1 month	+34.61%	+1.07%
3 months	+50.62%	+12.21%
6 months	+73.03%	+12.13%
1 year	+195.36%	+23.31%
5 years(CAGR)	+6.58%	+9.13%
10 years(CAGR)	N/A	+9.99%
Max(CAGR)	+6.58%	+8.74%

Winner

AMLX

+34.61%

EFSC

+1.07%

Winner

AMLX

+50.62%

EFSC

+12.21%

Winner

AMLX

+73.03%

EFSC

+12.13%

Winner

AMLX

+195.36%

EFSC

+23.31%

5Y(CAGR)

AMLX

+6.58%

Winner

EFSC

+9.13%

10Y(CAGR)

AMLX

N/A

EFSC

+9.99%

Max(CAGR)

AMLX

+6.58%

Winner

EFSC

+8.74%

AMLX vs EFSC - Annual Returns (2003 - 2026)

Returns include dividend reinvestment.

Year	AMLX	EFSC
2026	+111.82%	+24.24%
2025	+208.95%	-0.49%
2024	-74.75%	+27.99%
2023	-59.09%	-6.12%
2022	+104.48%	+4.51%
2021	N/A	+38.15%
2020	N/A	-25.67%
2019	N/A	+28.34%
2018	N/A	-15.75%
2017	N/A	+6.98%
2016	N/A	+55.43%
2015	N/A	+47.16%
2014	N/A	+0.18%
2013	N/A	+49.46%
2012	N/A	-12.90%
2011	N/A	+37.95%
2010	N/A	+33.67%
2009	N/A	-46.74%
2008	N/A	-32.40%
2007	N/A	-21.55%
2006	N/A	+42.44%
2005	N/A	+23.41%
2004	N/A	+34.06%
2003	N/A	+4.49%

AMLX vs EFSC Drawdown Comparison

The maximum drawdown for AMLX was -96.04%, occurring on Jun 18, 2024. This drawdown has not yet recovered.

The maximum drawdown for EFSC was -77.62%, occurring on Dec 22, 2009. Recovery took 2261 trading sessions.

The current AMLX drawdown is -40.90%. The current EFSC drawdown is -3.12%.

Rank	AMLX	EFSC
#1	-96.04% Jan 27, 2023 - Jun 18, 2024	-77.62% Oct 30, 2006 - Oct 23, 2015
#2	-79.18% Feb 28, 2022 - Oct 10, 2022	-57.20% Jul 26, 2018 - Feb 1, 2023
#3	-17.59% Feb 1, 2022 - Feb 18, 2022	-38.77% Feb 7, 2023 - Jul 26, 2024
#4	-15.23% Dec 1, 2022 - Jan 24, 2023	-25.04% Feb 6, 2025 - Aug 27, 2025
#5	-13.39% Oct 26, 2022 - Nov 25, 2022	-24.19% Jul 11, 2005 - Feb 14, 2006
#6	-12.97% Jan 19, 2022 - Jan 31, 2022	-19.79% Feb 22, 2017 - Nov 29, 2017
#7	-7.90% Jan 13, 2022 - Jan 19, 2022	-16.30% Nov 10, 2015 - Aug 5, 2016
#8	-7.47% Jan 7, 2022 - Jan 11, 2022	-15.27% Aug 27, 2025 - Feb 17, 2026
#9	-5.42% Nov 25, 2022 - Dec 1, 2022	-14.01% Feb 20, 2026 - May 26, 2026
#10	-3.44% Feb 22, 2022 - Feb 24, 2022	-12.67% Apr 5, 2006 - Aug 16, 2006
#11	-3.19% Oct 10, 2022 - Oct 13, 2022	-12.43% Feb 8, 2005 - Jun 6, 2005
#12	-2.79% Oct 13, 2022 - Oct 17, 2022	-11.54% Jul 26, 2024 - Oct 17, 2024
#13	-1.41% Oct 18, 2022 - Oct 21, 2022	-11.48% Nov 25, 2024 - Feb 5, 2025
#14	-1.06% Jan 25, 2023 - Jan 27, 2023	-11.21% Dec 29, 2016 - Feb 13, 2017
#15	N/A	-10.00% Apr 27, 2004 - Jun 7, 2004