AKUS vs PRME

Comparison between Akouos Inc (AKUS, Company) and Prime Medicine Inc (PRME, Company).

AKUS vs PRME - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	AKUS(COMPANY)	PRME(COMPANY)
Market Cap	$490M	$489M
Max Drawdown	90.86%	94.55%
Sharpe Ratio	0.86	1.05
5Y Beta	N/A	2.13
Industry	N/A	Biotechnology
P/E Ratio	-5.30	-2.26
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	-15.58%	-32.43%
P/S Ratio	N/A	121.34
P/B Ratio	2.71	6.38

Market Cap

Winner

AKUS

$490M

PRME

$489M

Max Drawdown

Winner

AKUS

90.86%

PRME

94.55%

Sharpe Ratio

AKUS

0.86

Winner

PRME

1.05

5Y Beta

AKUS

N/A

PRME

2.13

Industry

AKUS

N/A

PRME

Biotechnology

P/E Ratio

Winner

AKUS

-5.30

PRME

-2.26

Debt to Equity

AKUS

0.00%

PRME

0.00%

Free Cash Flow Yield

Winner

AKUS

-15.58%

PRME

-32.43%

P/S Ratio

AKUS

N/A

PRME

121.34

P/B Ratio

Winner

AKUS

2.71

PRME

6.38

AKUS vs PRME - Historical Returns

Returns include dividend reinvestment.

Period	AKUS	PRME
1 month	+0.00%	-15.91%
3 months	+95.44%	-25.60%
6 months	+327.33%	-32.32%
1 year	+46.37%	+90.07%
Max(CAGR)	-18.12%	-37.48%

Winner

AKUS

+0.00%

PRME

-15.91%

Winner

AKUS

+95.44%

PRME

-25.60%

Winner

AKUS

+327.33%

PRME

-32.32%

AKUS

+46.37%

Winner

PRME

+90.07%

Max(CAGR)

Winner

AKUS

-18.12%

PRME

-37.48%

AKUS vs PRME - Annual Returns (2020 - 2026)

Returns include dividend reinvestment.

Year	AKUS	PRME
2026	N/A	-21.39%
2025	N/A	+16.05%
2024	N/A	-66.67%
2023	+0.00%	-49.49%
2022	+46.37%	+20.88%
2021	-56.25%	N/A
2020	-9.86%	N/A

AKUS vs PRME Drawdown Comparison

The maximum drawdown for AKUS was -90.86%, occurring on May 25, 2022. This drawdown has not yet recovered.

The maximum drawdown for PRME was -94.55%, occurring on Apr 8, 2025. This drawdown has not yet recovered.

The current AKUS drawdown is -50.63%. The current PRME drawdown is -86.86%.

Rank	AKUS	PRME
#1	-90.86% Sep 14, 2020 - May 25, 2022	-94.55% Nov 1, 2022 - Apr 8, 2025
#2	-14.22% Jun 30, 2020 - Aug 28, 2020	-3.55% Oct 21, 2022 - Oct 25, 2022
#3	-7.97% Sep 2, 2020 - Sep 8, 2020	N/A
#4	-4.37% Sep 9, 2020 - Sep 14, 2020	N/A
#5	-0.80% Aug 28, 2020 - Sep 1, 2020	N/A

Correlation

Correlation between AKUS and PRME is -0.66 which considered as a moderate negative correlation - the stocks show some tendency to move in opposite directions.

-0.66

-101