AKTX vs AMWL

Comparison between Akari Therapeutics Plc (AKTX, Company) and American Well Corporation - Class A (AMWL, Company).

Both AKTX and AMWL are from the Healthcare sector.

5-Year PerformanceAMWL has outperformed AKTX, delivering a return of -49.6% compared to -60.7%

AKTX vs AMWL - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	AKTX(COMPANY)	AMWL(COMPANY)
Market Cap	$148M	$140M
Max Drawdown	99.99%	99.56%
Sharpe Ratio	0.31	0.62
5Y Beta	0.65	1.32
Industry	Biotechnology	Health Information Services
P/E Ratio	-8.66	-1.57
PEG Ratio	0.00	N/A
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	-6.52%	-29.83%
P/S Ratio	478368.50	0.59
P/B Ratio	1.14	0.62

Market Cap

Winner

AKTX

$148M

AMWL

$140M

Max Drawdown

AKTX

99.99%

Winner

AMWL

99.56%

Sharpe Ratio

AKTX

0.31

Winner

AMWL

0.62

5Y Beta

Winner

AKTX

0.65

AMWL

1.32

Industry

AKTX

Biotechnology

AMWL

Health Information Services

P/E Ratio

Winner

AKTX

-8.66

AMWL

-1.57

PEG Ratio

AKTX

0.00

AMWL

N/A

Debt to Equity

AKTX

0.00%

AMWL

0.00%

Free Cash Flow Yield

Winner

AKTX

-6.52%

AMWL

-29.83%

P/S Ratio

AKTX

478368.50

Winner

AMWL

0.59

P/B Ratio

AKTX

1.14

Winner

AMWL

0.62

AKTX vs AMWL - Historical Returns

Returns include dividend reinvestment.

Period	AKTX	AMWL
1 month	+277.36%	+15.13%
3 months	+59.06%	+54.80%
6 months	-19.89%	+85.43%
1 year	-69.79%	+25.76%
5 years(CAGR)	-60.68%	-49.57%
10 years(CAGR)	-49.28%	N/A
Max(CAGR)	-50.54%	-49.91%

Winner

AKTX

+277.36%

AMWL

+15.13%

Winner

AKTX

+59.06%

AMWL

+54.80%

AKTX

-19.89%

Winner

AMWL

+85.43%

AKTX

-69.79%

Winner

AMWL

+25.76%

5Y(CAGR)

AKTX

-60.68%

Winner

AMWL

-49.57%

10Y(CAGR)

AKTX

-49.28%

AMWL

N/A

Max(CAGR)

AKTX

-50.54%

Winner

AMWL

-49.91%

AKTX vs AMWL - Annual Returns (2015 - 2026)

Returns include dividend reinvestment.

Year	AKTX	AMWL
2026	+13.53%	+79.69%
2025	-76.12%	-30.26%
2024	-57.88%	-75.00%
2023	-68.39%	-47.16%
2022	-68.88%	-54.28%
2021	-17.13%	-76.36%
2020	+6.32%	+9.80%
2019	+5.11%	N/A
2018	-64.24%	N/A
2017	-42.27%	N/A
2016	-48.42%	N/A
2015	-53.97%	N/A

AKTX vs AMWL Drawdown Comparison

The maximum drawdown for AKTX was -99.99%, occurring on May 12, 2026. This drawdown has not yet recovered.

The maximum drawdown for AMWL was -99.56%, occurring on Nov 20, 2025. This drawdown has not yet recovered.

The current AKTX drawdown is -99.95%. The current AMWL drawdown is -98.98%.

Rank	AKTX	AMWL
#1	-99.99% Sep 21, 2015 - May 12, 2026	-99.56% Jan 27, 2021 - Nov 20, 2025
#2	N/A	-44.09% Oct 7, 2020 - Jan 27, 2021
#3	N/A	-4.28% Sep 30, 2020 - Oct 5, 2020
#4	N/A	-2.74% Sep 23, 2020 - Sep 30, 2020
#5	N/A	-1.17% Sep 17, 2020 - Sep 22, 2020