ADPT vs DNLI

Comparison between Adaptive Biotechnologies Corp (ADPT, Company) and Denali Therapeutics Inc (DNLI, Company).

Both ADPT and DNLI are from the Healthcare sector.

5-Year PerformanceADPT has outperformed DNLI, delivering a return of -8.3% compared to -18.6%

ADPT vs DNLI - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	ADPT(COMPANY)	DNLI(COMPANY)
Market Cap	$3.66B	$3.65B
Max Drawdown	96.55%	87.74%
Sharpe Ratio	1.28	1.00
5Y Beta	1.72	1.48
Industry	Diagnostics & Research	Biotechnology
P/E Ratio	-71.69	-6.87
PEG Ratio	N/A	-1.07
5Y EPS CAGR	-22.53%	N/A
Debt to Equity	60.35%	0.00%
Free Cash Flow Yield	-0.81%	-11.55%

Market Cap

Winner

ADPT

$3.66B

DNLI

$3.65B

Max Drawdown

ADPT

96.55%

Winner

DNLI

87.74%

Sharpe Ratio

Winner

ADPT

1.28

DNLI

1.00

5Y Beta

ADPT

1.72

Winner

DNLI

1.48

Industry

ADPT

Diagnostics & Research

DNLI

Biotechnology

P/E Ratio

Winner

ADPT

-71.69

DNLI

-6.87

PEG Ratio

ADPT

N/A

DNLI

-1.07

5Y EPS CAGR

ADPT

-22.53%

DNLI

N/A

Debt to Equity

ADPT

60.35%

Winner

DNLI

0.00%

Free Cash Flow Yield

Winner

ADPT

-0.81%

DNLI

-11.55%

ADPT vs DNLI - Historical Returns

Returns include dividend reinvestment.

Period	ADPT	DNLI
1 month	+31.16%	+3.60%
3 months	+57.60%	+6.18%
6 months	+28.80%	+22.58%
1 year	+107.05%	+62.46%
5 years(CAGR)	-8.26%	-18.55%
10 years(CAGR)	N/A	+0.82%
Max(CAGR)	-7.70%	+0.82%

Winner

ADPT

+31.16%

DNLI

+3.60%

Winner

ADPT

+57.60%

DNLI

+6.18%

Winner

ADPT

+28.80%

DNLI

+22.58%

Winner

ADPT

+107.05%

DNLI

+62.46%

5Y(CAGR)

Winner

ADPT

-8.26%

DNLI

-18.55%

10Y(CAGR)

ADPT

N/A

DNLI

+0.82%

Max(CAGR)

ADPT

-7.70%

Winner

DNLI

+0.82%

ADPT vs DNLI - Annual Returns (2017 - 2026)

Returns include dividend reinvestment.

Year	ADPT	DNLI
2026	+43.93%	+41.49%
2025	+162.36%	-20.78%
2024	+25.68%	-4.72%
2023	-37.18%	-22.33%
2022	-73.56%	-41.17%
2021	-49.74%	-37.06%
2020	+101.33%	+411.04%
2019	-25.76%	-9.88%
2018	N/A	+28.08%
2017	N/A	-27.09%

ADPT vs DNLI Drawdown Comparison

The maximum drawdown for ADPT was -96.55%, occurring on Apr 18, 2024. This drawdown has not yet recovered.

The maximum drawdown for DNLI was -87.74%, occurring on Apr 8, 2025. This drawdown has not yet recovered.

The current ADPT drawdown is -66.19%. The current DNLI drawdown is -75.40%.

Rank	ADPT	DNLI
#1	-96.55% Jan 22, 2021 - Apr 18, 2024	-87.74% Dec 22, 2020 - Apr 8, 2025
#2	-68.30% Sep 4, 2019 - Dec 10, 2020	-49.76% Feb 16, 2018 - Apr 2, 2019
#3	-27.29% Jun 28, 2019 - Aug 29, 2019	-49.54% Apr 10, 2019 - Jun 2, 2020
#4	-14.85% Dec 23, 2020 - Jan 14, 2021	-29.88% Dec 8, 2017 - Jan 22, 2018
#5	-2.05% Dec 14, 2020 - Dec 17, 2020	-19.74% Jun 3, 2020 - Aug 6, 2020
#6	-0.85% Jan 14, 2021 - Jan 19, 2021	-19.58% Jan 29, 2018 - Feb 16, 2018
#7	-0.71% Jan 19, 2021 - Jan 22, 2021	-13.33% Nov 12, 2020 - Dec 4, 2020
#8	N/A	-11.16% Aug 10, 2020 - Aug 25, 2020
#9	N/A	-10.43% Sep 17, 2020 - Oct 7, 2020
#10	N/A	-10.33% Oct 13, 2020 - Oct 27, 2020
#11	N/A	-9.64% Aug 25, 2020 - Sep 14, 2020
#12	N/A	-7.28% Oct 28, 2020 - Nov 4, 2020
#13	N/A	-3.20% Jan 23, 2018 - Jan 26, 2018
#14	N/A	-2.37% Apr 3, 2019 - Apr 5, 2019
#15	N/A	-1.33% Dec 16, 2020 - Dec 18, 2020