ACTU vs PSTV

Comparison between Actuate Therapeutics Inc (ACTU, Company) and Plus Therapeutics Inc (PSTV, Company).

Both ACTU and PSTV are from the Healthcare sector.

ACTU vs PSTV - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	ACTU(COMPANY)	PSTV(COMPANY)
Market Cap	$26M	$25M
Max Drawdown	91.09%	100.00%
Sharpe Ratio	-1.41	-0.44
5Y Beta	1.02	0.00
Industry	Biotechnology	Biotechnology
P/E Ratio	-1.13	-2.44
Forward P/E	N/A	0.97
PEG Ratio	N/A	2.45
5Y EPS CAGR	N/A	-25.42%
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	-76.56%	-87.21%
P/S Ratio	N/A	4.82
P/B Ratio	6.80	2.16

Market Cap

Winner

ACTU

$26M

PSTV

$25M

Max Drawdown

Winner

ACTU

91.09%

PSTV

100.00%

Sharpe Ratio

ACTU

-1.41

Winner

PSTV

-0.44

5Y Beta

ACTU

1.02

Winner

PSTV

0.00

Industry

ACTU

Biotechnology

PSTV

Biotechnology

P/E Ratio

ACTU

-1.13

Winner

PSTV

-2.44

Forward P/E

ACTU

N/A

PSTV

0.97

PEG Ratio

ACTU

N/A

PSTV

2.45

5Y EPS CAGR

ACTU

N/A

PSTV

-25.42%

Debt to Equity

ACTU

0.00%

PSTV

0.00%

Free Cash Flow Yield

Winner

ACTU

-76.56%

PSTV

-87.21%

P/S Ratio

ACTU

N/A

PSTV

4.82

P/B Ratio

ACTU

6.80

Winner

PSTV

2.16

ACTU vs PSTV - Historical Returns

Returns include dividend reinvestment.

Period	ACTU	PSTV
1 month	-23.53%	-16.48%
3 months	-60.20%	-40.55%
6 months	-75.16%	-35.99%
1 year	-83.91%	-68.07%
5 years(CAGR)	N/A	-65.18%
10 years(CAGR)	N/A	-68.71%
Max(CAGR)	-63.87%	-46.38%

ACTU

-23.53%

Winner

PSTV

-16.48%

ACTU

-60.20%

Winner

PSTV

-40.55%

ACTU

-75.16%

Winner

PSTV

-35.99%

ACTU

-83.91%

Winner

PSTV

-68.07%

5Y(CAGR)

ACTU

N/A

PSTV

-65.18%

10Y(CAGR)

ACTU

N/A

PSTV

-68.71%

Max(CAGR)

ACTU

-63.87%

Winner

PSTV

-46.38%

ACTU vs PSTV - Annual Returns (2000 - 2026)

Returns include dividend reinvestment.

Year	ACTU	PSTV
2026	-80.60%	-73.69%
2025	-23.12%	-56.58%
2024	-7.55%	-37.84%
2023	N/A	-62.40%
2022	N/A	-70.94%
2021	N/A	-50.24%
2020	N/A	-23.77%
2019	N/A	-85.00%
2018	N/A	-90.00%
2017	N/A	-81.25%
2016	N/A	-46.23%
2015	N/A	-64.42%
2014	N/A	-80.61%
2013	N/A	-9.51%
2012	N/A	+22.81%
2011	N/A	-59.18%
2010	N/A	-16.56%
2009	N/A	+69.44%
2008	N/A	-40.92%
2007	N/A	-5.47%
2006	N/A	-21.01%
2005	N/A	+248.74%
2004	N/A	-9.84%
2003	N/A	-23.75%
2002	N/A	+19.05%
2001	N/A	-72.77%
2000	N/A	+0.00%

ACTU vs PSTV Drawdown Comparison

The maximum drawdown for ACTU was -91.09%, occurring on Jul 28, 2026. This drawdown has not yet recovered.

The maximum drawdown for PSTV was -100.00%, occurring on Apr 7, 2026. This drawdown has not yet recovered.

The current ACTU drawdown is -90.17%. The current PSTV drawdown is -100.00%.

Rank	ACTU	PSTV
#1	-91.09% May 30, 2025 - Jul 28, 2026	-100.00% Nov 16, 2000 - Apr 7, 2026
#2	-40.82% Jan 23, 2025 - May 30, 2025	N/A
#3	-36.61% Aug 14, 2024 - Oct 28, 2024	N/A
#4	-26.65% Oct 28, 2024 - Jan 21, 2025	N/A