ACIU vs PROF

Comparison between AC Immune SA (ACIU, Company) and Profound Medical Corp (PROF, Company).

Both ACIU and PROF are from the Healthcare sector.

5-Year PerformancePROF has outperformed ACIU, delivering a return of -15.2% compared to -17.3%

ACIU vs PROF - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	ACIU(COMPANY)	PROF(COMPANY)
Market Cap	$254M	$253M
Max Drawdown	92.33%	99.74%
Sharpe Ratio	0.63	0.61
5Y Beta	1.02	0.78
Industry	Biotechnology	Medical Devices
P/E Ratio	-4.72	-7.34
Forward P/E	11.24	N/A
5Y EPS CAGR	-13.32%	N/A
Debt to Equity	11.66%	18.10%
Free Cash Flow Yield	-17.35%	-14.33%

Market Cap

Winner

ACIU

$254M

PROF

$253M

Max Drawdown

Winner

ACIU

92.33%

PROF

99.74%

Sharpe Ratio

Winner

ACIU

0.63

PROF

0.61

5Y Beta

ACIU

1.02

Winner

PROF

0.78

Industry

ACIU

Biotechnology

PROF

Medical Devices

P/E Ratio

ACIU

-4.72

Winner

PROF

-7.34

Forward P/E

ACIU

11.24

PROF

N/A

5Y EPS CAGR

ACIU

-13.32%

PROF

N/A

Debt to Equity

Winner

ACIU

11.66%

PROF

18.10%

Free Cash Flow Yield

ACIU

-17.35%

Winner

PROF

-14.33%

ACIU vs PROF - Historical Returns

Returns include dividend reinvestment.

Period	ACIU	PROF
1 month	+4.90%	-6.71%
3 months	-9.51%	-6.06%
6 months	-14.05%	+1.06%
1 year	+16.82%	+22.39%
5 years(CAGR)	-17.29%	-15.25%
10 years(CAGR)	-16.71%	-5.03%
Max(CAGR)	-16.71%	-4.07%

Winner

ACIU

+4.90%

PROF

-6.71%

ACIU

-9.51%

Winner

PROF

-6.06%

ACIU

-14.05%

Winner

PROF

+1.06%

ACIU

+16.82%

Winner

PROF

+22.39%

5Y(CAGR)

ACIU

-17.29%

Winner

PROF

-15.25%

10Y(CAGR)

ACIU

-16.71%

Winner

PROF

-5.03%

Max(CAGR)

ACIU

-16.71%

Winner

PROF

-4.07%

ACIU vs PROF - Annual Returns (2016 - 2026)

Returns include dividend reinvestment.

Year	ACIU	PROF
2026	-23.51%	-12.92%
2025	+10.18%	-0.38%
2024	-42.43%	-5.53%
2023	+126.24%	-23.17%
2022	-60.47%	-1.00%
2021	-6.95%	-48.86%
2020	-40.30%	+94.15%
2019	-16.63%	+124.66%
2018	-29.21%	-35.35%
2017	-1.61%	-17.98%
2016	-17.11%	-21.88%

ACIU vs PROF Drawdown Comparison

The maximum drawdown for ACIU was -92.33%, occurring on Apr 10, 2025. This drawdown has not yet recovered.

The maximum drawdown for PROF was -99.74%, occurring on Jul 19, 2017. Recovery took 639 trading sessions.

The current ACIU drawdown is -86.68%. The current PROF drawdown is -76.25%.

Rank	ACIU	PROF
#1	-92.33% Sep 28, 2016 - Apr 10, 2025	-99.74% Aug 18, 2016 - Sep 9, 2019
#2	N/A	-88.68% Feb 5, 2021 - Oct 26, 2022
#3	N/A	-65.10% Feb 7, 2020 - Nov 30, 2020
#4	N/A	-45.76% Sep 9, 2019 - Dec 26, 2019
#5	N/A	-17.15% Dec 26, 2019 - Jan 13, 2020
#6	N/A	-11.55% Dec 1, 2020 - Dec 21, 2020
#7	N/A	-10.22% Dec 22, 2020 - Jan 6, 2021
#8	N/A	-8.40% Jan 16, 2020 - Jan 28, 2020
#9	N/A	-7.59% Jul 6, 2016 - Aug 10, 2016
#10	N/A	-7.55% Jan 26, 2021 - Feb 4, 2021
#11	N/A	-5.31% Jan 15, 2021 - Jan 20, 2021
#12	N/A	-3.68% Jan 11, 2021 - Jan 15, 2021
#13	N/A	-2.55% Jan 13, 2020 - Jan 15, 2020
#14	N/A	-1.63% Jan 21, 2021 - Jan 25, 2021